Tratamento de vasculopatia livedóide com imunoglobulina intravenosa

A vasculopatia livedóide apresenta-se com dor e úlceras de cicatrização lenta em membros inferiores, e fisiopatologia obscura. As estratégias terapêuticas incluem cicatrizantes, antiinflamatórios e imunossupressores, sem relatos de benefício permanente. Administrou-se imunoglobulina em paciente refr...

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Veröffentlicht in:Anais brasileiros de dermatología 2008-08, Vol.83 (4), p.372-374
Hauptverfasser: Sobral Filho, Jader Freire, Valdek, Milane Caroline de Oliveira, Rodrigues, Luiza Toscano Dias
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container_issue 4
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container_title Anais brasileiros de dermatología
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creator Sobral Filho, Jader Freire
Valdek, Milane Caroline de Oliveira
Rodrigues, Luiza Toscano Dias
description A vasculopatia livedóide apresenta-se com dor e úlceras de cicatrização lenta em membros inferiores, e fisiopatologia obscura. As estratégias terapêuticas incluem cicatrizantes, antiinflamatórios e imunossupressores, sem relatos de benefício permanente. Administrou-se imunoglobulina em paciente refratário a outras terapias e avaliou-se o comprometimento da pele antes e depois por meio de escore clínico. Houve regressão significativa das lesões. A droga foi bem tolerada, e a terapia foi finalizada. Livedoid vasculopathy presents with pain and slowly healing ulcerations of the lower limbs, and has obscure pathophysiology. Usual therapeutics include rheologic, anti-inflammatory and immunosuppressing agents with no reports of permanent benefits. Immunoglobulin was administered to a patient who was refractory to other treatments and skin involvement was assessed by means of clinical score before and after treatment. There was a significant healing of the lesions. Imunoglobulim was well tolerated and therapy was discontinued.
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