Sodium butyrate does not decrease the evolution of precancerous lesions in rats

To evaluate the preventive effect of sodium butyrate in the appearance of aberrant crypt foci (ACF) in rats after induction with the carcinogen 1,2-dimethylhydrazine (DMH). Forty Wistar rats were separated into four groups (n=10) distributed as follows: control 1, control 2, butyrate 1 and butyrate...

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Veröffentlicht in:	Acta cirurgica brasileira 2010-12, Vol.25 (6), p.507-512
Hauptverfasser:	Silva, Fernanda Guimarães Drummond E, Penido, Luisa Costa Penna, Valente, Flávia Xavier, Mendes, Maria Carolina Santos, Rosa, Damiana Diniz, Glória, Maria Beatriz Abreu, Peluzio, Maria do Carmo Gouveia
Format:	Artikel
Sprache:	eng
Schlagworte:	1,2-Dimethylhydrazine Aberrant Crypt Foci - pathology Animals Butyrates - adverse effects Butyrates - pharmacology Carcinogens Colorectal Neoplasms - prevention & control Disease Models, Animal Fatty Acids - analysis Feces - chemistry Intestine, Large - metabolism Intestine, Large - pathology Male Polyamines - metabolism Precancerous Conditions - chemically induced Precancerous Conditions - prevention & control Random Allocation Rats Rats, Wistar
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