Alginate/Chitosan Associates a Platelet-rich in Fibrin Exudates as Drug Delivery Systems in Wounds: a Mini-Review
Abstract The use of biopolymers and platelet-rich fibrin (PRF) is currently investigated as an excellent application biomaterial in the tissue engineering field. Natural biomaterials with application potential in tissue engineering and regenerative medicine are due to their characteristics in biocom...
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Veröffentlicht in: | Brazilian Archives of Biology and Technology 2023-01, Vol.66 |
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container_title | Brazilian Archives of Biology and Technology |
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creator | Barbosa, Carlos de Almeida Simeoni, Rossana Baggio Gamba, Luize Kremer Ribeiro, Victoria Stadler Tasca Cardoso, Marco André Cunha, Ricardo Correa Souza, Clayton Fernandes de Francisco, Júlio Cesar Guarita-Souza, Luiz Cesar Fernandes, Beatriz Luci |
description | Abstract The use of biopolymers and platelet-rich fibrin (PRF) is currently investigated as an excellent application biomaterial in the tissue engineering field. Natural biomaterials with application potential in tissue engineering and regenerative medicine are due to their characteristics in biocompatibility, biodegradability, and mechanical characteristic. Though, the basic knowledge of three‐dimensional fibrin scaffold and chitosan/alginate processing technology combined with an understanding of the physical-chemical properties of this natural biomaterial is necessary for proper application in regenerative medicine and tissue engineering. This mini review summarizes the information on the composition of chitosan/alginate and PRF in medical area and discusses recent developments with a special focus on its use for the application of drug delivery. The most important advances and stimulating applications are studies in regenerative medicine and tissue engineering, for wound healing to treat burns, tumor treatment, nanoparticle carriers, and drug delivery systems. |
doi_str_mv | 10.1590/1678-4324-2023220880 |
format | Article |
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Natural biomaterials with application potential in tissue engineering and regenerative medicine are due to their characteristics in biocompatibility, biodegradability, and mechanical characteristic. Though, the basic knowledge of three‐dimensional fibrin scaffold and chitosan/alginate processing technology combined with an understanding of the physical-chemical properties of this natural biomaterial is necessary for proper application in regenerative medicine and tissue engineering. This mini review summarizes the information on the composition of chitosan/alginate and PRF in medical area and discusses recent developments with a special focus on its use for the application of drug delivery. 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Natural biomaterials with application potential in tissue engineering and regenerative medicine are due to their characteristics in biocompatibility, biodegradability, and mechanical characteristic. Though, the basic knowledge of three‐dimensional fibrin scaffold and chitosan/alginate processing technology combined with an understanding of the physical-chemical properties of this natural biomaterial is necessary for proper application in regenerative medicine and tissue engineering. This mini review summarizes the information on the composition of chitosan/alginate and PRF in medical area and discusses recent developments with a special focus on its use for the application of drug delivery. 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subjects | Drug delivery systems, chitosan/alginate, platelet-rich fibrin Regeneration Wound healing |
title | Alginate/Chitosan Associates a Platelet-rich in Fibrin Exudates as Drug Delivery Systems in Wounds: a Mini-Review |
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