Influence of Fluoridated Groundwater and 1,100 Ppm Fluoride Dentifrice on Biomarkers of Exposure to Fluoride
This research aimed to determine the influence of fluoridated groundwater and 1,100 ppm fluoride dentifrice on biomarkers of exposure to fluoride in preschoolers. A cross-sectional study was performed on thirty preschoolers recruited from naturally fluoridated and non-fluoridated areas (n=15). Total...
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| Veröffentlicht in: | Brazilian dental journal 2018-09, Vol.29 (5), p.475-482 |
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| container_title | Brazilian dental journal |
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| creator | Sousa, Emerson Tavares de Alves, Vanessa Feitosa Maia, Fabiana Barros Marinho Nobre-Dos-Santos, Marinês Forte, Franklin Delano Soares Sampaio, Fábio Correia |
| description | This research aimed to determine the influence of fluoridated groundwater and 1,100 ppm fluoride dentifrice on biomarkers of exposure to fluoride in preschoolers. A cross-sectional study was performed on thirty preschoolers recruited from naturally fluoridated and non-fluoridated areas (n=15). Total Daily Fluoride Intake (TDFI) from diet and dentifrice, and Daily Urinary Fluoride Excretion (DUFE) was measured over 24 h. Nails samples were collected twice during 30 days. Fluoride analyses were performed using a fluoride-ion-specific electrode. Data were evaluated using the Student and paired t-test, Pearson correlation analysis, multiple linear regression analysis (α≤0.05). Fluoridated groundwater and dentifrice were the dominant sources (r2 > 0.83) of TDFI in children from a naturally fluoridated and a non-fluoridated area, respectively. A positive correlation between TDFI and DUFE (r=0.50), and between [F] in fingernails and toenails (r=0.60) were found in children from a naturally fluoridated area. The [F] in nails of finger and toe were not correlated to TDFI. The consumption of fluoridated groundwater influenced the fluoride concentration in urine. In addition, the use of 1,100 ppm fluoride dentifrice did not influence the fluoride concentration in urine and fingernails. |
| doi_str_mv | 10.1590/0103-6440201801959 |
| format | Article |
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A cross-sectional study was performed on thirty preschoolers recruited from naturally fluoridated and non-fluoridated areas (n=15). Total Daily Fluoride Intake (TDFI) from diet and dentifrice, and Daily Urinary Fluoride Excretion (DUFE) was measured over 24 h. Nails samples were collected twice during 30 days. Fluoride analyses were performed using a fluoride-ion-specific electrode. Data were evaluated using the Student and paired t-test, Pearson correlation analysis, multiple linear regression analysis (α≤0.05). Fluoridated groundwater and dentifrice were the dominant sources (r2 > 0.83) of TDFI in children from a naturally fluoridated and a non-fluoridated area, respectively. A positive correlation between TDFI and DUFE (r=0.50), and between [F] in fingernails and toenails (r=0.60) were found in children from a naturally fluoridated area. The [F] in nails of finger and toe were not correlated to TDFI. The consumption of fluoridated groundwater influenced the fluoride concentration in urine. In addition, the use of 1,100 ppm fluoride dentifrice did not influence the fluoride concentration in urine and fingernails.</description><identifier>ISSN: 0103-6440</identifier><identifier>EISSN: 1806-4760</identifier><identifier>DOI: 10.1590/0103-6440201801959</identifier><identifier>PMID: 30517447</identifier><language>eng</language><publisher>Brazil</publisher><subject>Biomarkers - analysis ; Brazil - epidemiology ; Child, Preschool ; Cross-Sectional Studies ; Dentifrices - chemistry ; Female ; Fluoridation ; Fluorides - analysis ; Fluorosis, Dental - epidemiology ; Groundwater ; Humans ; Male ; Nails - chemistry ; Urinalysis</subject><ispartof>Brazilian dental journal, 2018-09, Vol.29 (5), p.475-482</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3019-5ccc2f90c7f8a43bc43dacc4eb0e6b9a341f62b56eaa65cb3e44832029c74f343</citedby><cites>FETCH-LOGICAL-c3019-5ccc2f90c7f8a43bc43dacc4eb0e6b9a341f62b56eaa65cb3e44832029c74f343</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30517447$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sousa, Emerson Tavares de</creatorcontrib><creatorcontrib>Alves, Vanessa Feitosa</creatorcontrib><creatorcontrib>Maia, Fabiana Barros Marinho</creatorcontrib><creatorcontrib>Nobre-Dos-Santos, Marinês</creatorcontrib><creatorcontrib>Forte, Franklin Delano Soares</creatorcontrib><creatorcontrib>Sampaio, Fábio Correia</creatorcontrib><title>Influence of Fluoridated Groundwater and 1,100 Ppm Fluoride Dentifrice on Biomarkers of Exposure to Fluoride</title><title>Brazilian dental journal</title><addtitle>Braz Dent J</addtitle><description>This research aimed to determine the influence of fluoridated groundwater and 1,100 ppm fluoride dentifrice on biomarkers of exposure to fluoride in preschoolers. A cross-sectional study was performed on thirty preschoolers recruited from naturally fluoridated and non-fluoridated areas (n=15). Total Daily Fluoride Intake (TDFI) from diet and dentifrice, and Daily Urinary Fluoride Excretion (DUFE) was measured over 24 h. Nails samples were collected twice during 30 days. Fluoride analyses were performed using a fluoride-ion-specific electrode. Data were evaluated using the Student and paired t-test, Pearson correlation analysis, multiple linear regression analysis (α≤0.05). Fluoridated groundwater and dentifrice were the dominant sources (r2 > 0.83) of TDFI in children from a naturally fluoridated and a non-fluoridated area, respectively. A positive correlation between TDFI and DUFE (r=0.50), and between [F] in fingernails and toenails (r=0.60) were found in children from a naturally fluoridated area. The [F] in nails of finger and toe were not correlated to TDFI. The consumption of fluoridated groundwater influenced the fluoride concentration in urine. In addition, the use of 1,100 ppm fluoride dentifrice did not influence the fluoride concentration in urine and fingernails.</description><subject>Biomarkers - analysis</subject><subject>Brazil - epidemiology</subject><subject>Child, Preschool</subject><subject>Cross-Sectional Studies</subject><subject>Dentifrices - chemistry</subject><subject>Female</subject><subject>Fluoridation</subject><subject>Fluorides - analysis</subject><subject>Fluorosis, Dental - epidemiology</subject><subject>Groundwater</subject><subject>Humans</subject><subject>Male</subject><subject>Nails - chemistry</subject><subject>Urinalysis</subject><issn>0103-6440</issn><issn>1806-4760</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkEFOwzAQRS0EoqFwARbIByAwjidJvYTSlkqVYAHryHHGUiCNI7sRcHsSlVZiNbP472vmMXYt4E6kCu5BgIwzREhAzECoVJ2waNiyGPMMTll0DEzYRQgfMARRqnM2kZCKHDGPWLNubdNTa4g7y5dN73xd6R1VfOVd31Zfw-65bisubgUAf-22hxTxJ2p3tfX1CLf8sXZb7T_Jh7Fq8d250HviO3cELtmZ1U2gq785Ze_Lxdv8Od68rNbzh01s5PBGnBpjEqvA5HamUZYGZaWNQSqBslJpicJmSZlmpHWWmlIS4kwmkCiTo5UopyzZ9xrvQvBki87Xw20_hYBiVFeMZop_6gboZg91fbml6ogcXMlftAFphg</recordid><startdate>201809</startdate><enddate>201809</enddate><creator>Sousa, Emerson Tavares de</creator><creator>Alves, Vanessa Feitosa</creator><creator>Maia, Fabiana Barros Marinho</creator><creator>Nobre-Dos-Santos, Marinês</creator><creator>Forte, Franklin Delano Soares</creator><creator>Sampaio, Fábio Correia</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>201809</creationdate><title>Influence of Fluoridated Groundwater and 1,100 Ppm Fluoride Dentifrice on Biomarkers of Exposure to Fluoride</title><author>Sousa, Emerson Tavares de ; Alves, Vanessa Feitosa ; Maia, Fabiana Barros Marinho ; Nobre-Dos-Santos, Marinês ; Forte, Franklin Delano Soares ; Sampaio, Fábio Correia</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3019-5ccc2f90c7f8a43bc43dacc4eb0e6b9a341f62b56eaa65cb3e44832029c74f343</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Biomarkers - analysis</topic><topic>Brazil - epidemiology</topic><topic>Child, Preschool</topic><topic>Cross-Sectional Studies</topic><topic>Dentifrices - chemistry</topic><topic>Female</topic><topic>Fluoridation</topic><topic>Fluorides - analysis</topic><topic>Fluorosis, Dental - epidemiology</topic><topic>Groundwater</topic><topic>Humans</topic><topic>Male</topic><topic>Nails - chemistry</topic><topic>Urinalysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sousa, Emerson Tavares de</creatorcontrib><creatorcontrib>Alves, Vanessa Feitosa</creatorcontrib><creatorcontrib>Maia, Fabiana Barros Marinho</creatorcontrib><creatorcontrib>Nobre-Dos-Santos, Marinês</creatorcontrib><creatorcontrib>Forte, Franklin Delano Soares</creatorcontrib><creatorcontrib>Sampaio, Fábio Correia</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Brazilian dental journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sousa, Emerson Tavares de</au><au>Alves, Vanessa Feitosa</au><au>Maia, Fabiana Barros Marinho</au><au>Nobre-Dos-Santos, Marinês</au><au>Forte, Franklin Delano Soares</au><au>Sampaio, Fábio Correia</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Influence of Fluoridated Groundwater and 1,100 Ppm Fluoride Dentifrice on Biomarkers of Exposure to Fluoride</atitle><jtitle>Brazilian dental journal</jtitle><addtitle>Braz Dent J</addtitle><date>2018-09</date><risdate>2018</risdate><volume>29</volume><issue>5</issue><spage>475</spage><epage>482</epage><pages>475-482</pages><issn>0103-6440</issn><eissn>1806-4760</eissn><abstract>This research aimed to determine the influence of fluoridated groundwater and 1,100 ppm fluoride dentifrice on biomarkers of exposure to fluoride in preschoolers. A cross-sectional study was performed on thirty preschoolers recruited from naturally fluoridated and non-fluoridated areas (n=15). Total Daily Fluoride Intake (TDFI) from diet and dentifrice, and Daily Urinary Fluoride Excretion (DUFE) was measured over 24 h. Nails samples were collected twice during 30 days. Fluoride analyses were performed using a fluoride-ion-specific electrode. Data were evaluated using the Student and paired t-test, Pearson correlation analysis, multiple linear regression analysis (α≤0.05). Fluoridated groundwater and dentifrice were the dominant sources (r2 > 0.83) of TDFI in children from a naturally fluoridated and a non-fluoridated area, respectively. A positive correlation between TDFI and DUFE (r=0.50), and between [F] in fingernails and toenails (r=0.60) were found in children from a naturally fluoridated area. The [F] in nails of finger and toe were not correlated to TDFI. The consumption of fluoridated groundwater influenced the fluoride concentration in urine. In addition, the use of 1,100 ppm fluoride dentifrice did not influence the fluoride concentration in urine and fingernails.</abstract><cop>Brazil</cop><pmid>30517447</pmid><doi>10.1590/0103-6440201801959</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Biomarkers - analysis Brazil - epidemiology Child, Preschool Cross-Sectional Studies Dentifrices - chemistry Female Fluoridation Fluorides - analysis Fluorosis, Dental - epidemiology Groundwater Humans Male Nails - chemistry Urinalysis |
| title | Influence of Fluoridated Groundwater and 1,100 Ppm Fluoride Dentifrice on Biomarkers of Exposure to Fluoride |
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