Development of HPLC Optical Purity Testing Method of Denomapine and Application to Its Photostability

Direct enantiomer separation of denopamine (DP, active form: R (-)-form), which is an optically active and an orally administrable cardiotonic agent, was investigated by HPLC with β-cyclodextrin (β-CD) immobilized chiral stationary phases (CSPs). Successful enantiomer separation under the reversed-p...

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Veröffentlicht in:	CHROMATOGRAPHY 2023/10/20, Vol.44(3), pp.115-123
Hauptverfasser:	KAWABATA, Kohei, SANDANBATA, Mai, NISHI, Hiroyuki
Format:	Artikel
Sprache:	eng
Schlagworte:	Chiral HPLC Denopamine Optical purity testing Photostability Validation
Online-Zugang:	Volltext
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