Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) – a case report and a review of the latest scientific reports

Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) – a case report and a review of the latest scientific reports

The paper presents a case of a 61-year-old patient with chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS), along with a detailed description of the diagnostic and therapeutic process, as well as radiological records reflecting the evolution of l...

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Veröffentlicht in:Aktualności neurologiczne 2020-12, Vol.21 (4), p.178-186
Hauptverfasser: Dziubek, Dariusz, Rajchel, Mateusz, Stańko-Kałamarz, Barbara, Dziki, Mirosław
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Sprache:eng ; pol
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container_end_page 186
container_issue 4
container_start_page 178
container_title Aktualności neurologiczne
container_volume 21
creator Dziubek, Dariusz
Rajchel, Mateusz
Stańko-Kałamarz, Barbara
Dziki, Mirosław
description The paper presents a case of a 61-year-old patient with chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS), along with a detailed description of the diagnostic and therapeutic process, as well as radiological records reflecting the evolution of lesions depending on the steroid therapy used. We also refer to the latest literature reports on the aetiology, pathogenesis, diagnosis and treatment of this clinical entity, including its potential relationship with lymphoproliferative and lymphohistiocytic processes. Furthermore, we present a spectrum of diseases that can clinically and radiologically mimic CLIPPERS (CLIPPERS-mimics), along with the proposed differential diagnosis. Finally, the paper presents the recommended treatment strategy for both acute disease and a maintenance therapy, with particular emphasis on the role of steroid therapy.
doi_str_mv 10.15557/AN.2020.0022
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title Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) – a case report and a review of the latest scientific reports
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