Combined Neuroprotective Effects of Propofol and Dexmedetomidine on Endoplasmic Reticulum Stress-mediated Apoptosis in SH-SY5Y Cells

Propofol is a short-acting intravenous anesthetic agent. Dexmedetomidine, a highly selective α2-adrenergic receptor agonist, has a well-known sedative effect. Both agents exhibit cytoprotective effects in the nervous system under ischemic conditions. Recently, the combination of propofol plus dexmed...

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Veröffentlicht in:	The Showa University Journal of Medical Sciences 2016, Vol.28(3), pp.219-231
Hauptverfasser:	SOMEI, Masayuki, INAGAKI, Manami, OGUCHI, Tatsunori, ONO, Ran, TSUJI, Mayumi, OGUCHI, Katsuji
Format:	Artikel
Sprache:	eng
Schlagworte:	dexmedetomidine ER stress-mediated apoptosis neuroprotection propofol thapsigargin
Online-Zugang:	Volltext
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