Cancer chemotherapy based on targeting of cytotoxic peptide conjugates to their receptors on tumors

In view of non-specific toxicity of most chemotherapeutic agents against normal cells, the development of targeted chemotherapy is warranted. Efficient targeting of chemotherapeutic drugs to the cancerous area could be of great benefit for patients with advanced or metastatic tumors. Targeted cytoto...

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Veröffentlicht in:	European journal of endocrinology 1999-07, Vol.141 (1), p.1-14
Hauptverfasser:	SCHALLY, A. V, NAGY, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic agents Antineoplastic Agents - administration & dosage Antineoplastic Agents - chemistry Antineoplastic Agents - therapeutic use Biological and medical sciences Bombesin - analogs & derivatives Chemotherapy Female Gastrin-Releasing Peptide - analogs & derivatives Gonadotropin-Releasing Hormone - analogs & derivatives Humans Male Medical sciences Neoplasms - drug therapy Neoplasms - metabolism Pharmacology. Drug treatments Receptors, Cell Surface - metabolism Receptors, LHRH - metabolism Somatostatin - analogs & derivatives
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