FAM129A regulates autophagy in thyroid carcinomas in an oncogene-dependent manner

We previously proposed that high expression of FAM129A can be used as a thyroid carcinoma biomarker in preoperative diagnostic exams of thyroid nodules. Here, we identify that FAM129A expression is increased under nutrient and growth factor depletion in a normal thyroid cell line (PCCL3), overlappin...

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Veröffentlicht in:	Endocrine-related cancer 2019-01, Vol.26 (1), p.227-238
Hauptverfasser:	Nozima, Bruno Heidi, Mendes, Thais Biude, Pereira, Gustavo José da Silva, Araldi, Rodrigo Pinheiro, Iwamura, Edna Sadayo Miazato, Smaili, Soraya Soubhi, Carvalheira, Gianna Maria Griz, Cerutti, Janete Maria
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autophagy Biomarkers, Tumor - genetics Biomarkers, Tumor - metabolism Cell Line, Tumor Extracellular Signal-Regulated MAP Kinases - metabolism Humans Neoplasm Proteins - genetics Neoplasm Proteins - metabolism Proto-Oncogene Proteins c-akt - metabolism Proto-Oncogene Proteins c-ret - genetics Proto-Oncogene Proteins c-ret - metabolism Rats Thyroid Gland - metabolism Thyroid Neoplasms - genetics Thyroid Neoplasms - metabolism
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