Effect of Vitex agnus-castus and Salvia officinalis Extracts on Serum Lipids in Postmenopausal Women: An Randomized Clinical Trial

Objectives: This study aimed to investigate the effect of Vitex agnus-castus (VAC), and Salvia officinalis extracts on serum lipids in postmenopausal women referred to the Bone Densitometry Center, Namazi Hospital, Shiraz, Iran. Materials and Methods: This randomized clinical trial was conducted on...

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Veröffentlicht in:International journal of women's health and reproduction sciences 2024-04, Vol.12 (2), p.77-82
Hauptverfasser: Zeidabadi, Afsaneh, Jafari, Maryam, Emamghoreishi, Masoumeh, Sasani, Mohammad Resa, Akbarzadeh, Marzieh
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container_end_page 82
container_issue 2
container_start_page 77
container_title International journal of women's health and reproduction sciences
container_volume 12
creator Zeidabadi, Afsaneh
Jafari, Maryam
Emamghoreishi, Masoumeh
Sasani, Mohammad Resa
Akbarzadeh, Marzieh
description Objectives: This study aimed to investigate the effect of Vitex agnus-castus (VAC), and Salvia officinalis extracts on serum lipids in postmenopausal women referred to the Bone Densitometry Center, Namazi Hospital, Shiraz, Iran. Materials and Methods: This randomized clinical trial was conducted on 89 postmenopausal women in 2016 using random permuted blocks with a block size of 3 in the three groups, including the VAC group (3.2-4.8 mg/q8h), S. officinalis group (100 mg/q8h), and placebo group for three months. Women were finally compared in terms of low-density lipoprotein, triglycerides (TG), and highdensity lipoprotein before and after the intervention. Data were analyzed using SPSS-16 software. Descriptive statistical tests and paired t test were used to compare the groups. Results: A significant decrease in serum cholesterol, low-density lipoprotein, and triglycerides levels and also increase in mean serum high-density lipoprotein levels were observed in VAC and S. officinalis groups before and after the intervention (P = 0.0001). In comparison, no significant change was observed in serum level of any lipoproteins in the placebo group. Conclusions: Considering the decrease in the level of cholesterol, low-density lipoprotein, triglycerides, and increased highdensity lipoprotein after using VAC and S. officinalis in this study, these herbs can be proposed as blood lipid-lowering agents in postmenopausal women.
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title Effect of Vitex agnus-castus and Salvia officinalis Extracts on Serum Lipids in Postmenopausal Women: An Randomized Clinical Trial
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