Successful Strategy of Pre-implantation Genetic Testing for Beta-Thalassemia (c.17A>T Mutation)-Hb E Disease Using Multiplex Fluorescent PCR and Mini-Sequencing

Objectives: Hemoglobin E disease, c.26G>A variant of beta-globin gene, is the most common hemoglobinopathy in Asia. Compound heterozygotes inheriting Hb E disease and beta-thalassemia generate beta-thalassemia-Hb E disease with severe anemia. This study aimed to develop a pre-implantation genetic...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	International journal of women's health and reproduction sciences 2023-04, Vol.11 (2), p.58-64
Hauptverfasser:	Lattiwongsakorn, Worashorn, Jansaka, Natpat, Piyamongkol, Sirivipa, Pantasri, Tawiwan, Tongsong, Theera, Suriya, Wanwisa, Piyamongkol, Wirawit
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!