Heteromeric channels formed by TRPC 1, TRPC 4 and TRPC 5 define hippocampal synaptic transmission and working memory

Canonical transient receptor potential ( TRPC ) channels influence various neuronal functions. Using quantitative high‐resolution mass spectrometry, we demonstrate that TRPC 1, TRPC 4, and TRPC 5 assemble into heteromultimers with each other, but not with other TRP family members in the mouse brain...

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Veröffentlicht in:The EMBO journal 2017-09, Vol.36 (18), p.2770-2789
Hauptverfasser: Bröker‐Lai, Jenny, Kollewe, Astrid, Schindeldecker, Barbara, Pohle, Jörg, Nguyen Chi, Vivan, Mathar, Ilka, Guzman, Raul, Schwarz, Yvonne, Lai, Alan, Weißgerber, Petra, Schwegler, Herbert, Dietrich, Alexander, Both, Martin, Sprengel, Rolf, Draguhn, Andreas, Köhr, Georg, Fakler, Bernd, Flockerzi, Veit, Bruns, Dieter, Freichel, Marc
Format: Artikel
Sprache:eng
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