Evolution Of The Results Of 1500 Liver Transplantations Performed In The Department Of General, Transplant And Liver Surgery Medical University Of Warsaw
Liver transplantation is a well-established treatment of patients with end-stage liver disease and selected liver tumors. Remarkable progress has been made over the last years concerning nearly all of its aspects. was to evaluate the evolution of long-term outcomes after liver transplantations perfo...
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| Veröffentlicht in: | Polski przeglad chirurgiczny 2015-05, Vol.87 (5), p.221-230 |
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| creator | Krawczyk, Marek Grąt, Michał Grąt, Karolina Wronka, Karolina Krasnodębski, Maciej Stypułkowski, Jan Masior, Łukasz Hołówko, Wacław Ligocka, Joanna Nyckowski, Paweł Wróblewski, Tadeusz Paluszkiewicz, Rafał Patkowski, Waldemar Zieniewicz, Krzysztof Pączek, Leszek Milkiewicz, Piotr Ołdakowska-Jedynak, Urszula Najnigier, Bogusław Dudek, Krzysztof Remiszewski, Piotr Grzelak, Ireneusz Kornasiewicz, Oskar Kotulski, Marcin Smoter, Piotr Grodzicki, Mariusz Korba, Michał Kalinowski, Piotr Skalski, Michał Zając, Krzysztof Stankiewicz, Rafał Przybysz, Marta Cieślak, Bartosz Nazarewski, Łukasz Nowosad, Małgorzata Kobryń, Konrad Wasilewicz, Michał Raszeja-Wyszomirska, Joanna Piwowarska, Jolanta Giercuszkiewicz, Dorota Sańko-Resmer, Joanna Rejowski, Sławomir Szydłowska-Jakimiuk, Monika Górnicka, Barbara Wróblewska-Ziarkiewicz, Bogna Mazurkiewicz, Michał Niewiński, Grzegorz Pawlak, Jacek Pacho, Ryszard |
| description | Liver transplantation is a well-established treatment of patients with end-stage liver disease and selected liver tumors. Remarkable progress has been made over the last years concerning nearly all of its aspects.
was to evaluate the evolution of long-term outcomes after liver transplantations performed in the Department of General, Transplant and Liver Surgery (Medical University of Warsaw).
Data of 1500 liver transplantations performed between 1989 and 2014 were retrospectively analyzed. Transplantations were divided into 3 groups: group 1 including first 500 operations, group 2 including subsequent 500, and group 3 comprising the most recent 500. Five year overall and graft survival were set as outcome measures.
Increased number of transplantations performed at the site was associated with increased age of the recipients (p |
| doi_str_mv | 10.1515/pjs-2015-0046 |
| format | Article |
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was to evaluate the evolution of long-term outcomes after liver transplantations performed in the Department of General, Transplant and Liver Surgery (Medical University of Warsaw).
Data of 1500 liver transplantations performed between 1989 and 2014 were retrospectively analyzed. Transplantations were divided into 3 groups: group 1 including first 500 operations, group 2 including subsequent 500, and group 3 comprising the most recent 500. Five year overall and graft survival were set as outcome measures.
Increased number of transplantations performed at the site was associated with increased age of the recipients (p<0.001) and donors (p<0.001), increased rate of male recipients (p<0.001), and increased rate of piggyback operations (p<0.001), and decreased MELD (p<0.001), as well as decreased blood (p=0.006) and plasma (p<0.001) transfusions. Overall survival was 71.6% at 5 years in group 1, 74.5% at 5 years in group 2, and 85% at 2.9 years in group 3 (p=0.008). Improvement of overall survival was particularly observed for primary transplantations (p=0.004). Increased graft survival rates did not reach the level of significance (p=0.136).
Long-term outcomes after liver transplantations performed in the Department of General, Transplant and Liver Surgery are comparable to those achieved in the largest transplant centers worldwide and are continuously improving despite increasing recipient age and wider utilization of organs procured from older donors.]]></description><identifier>ISSN: 0032-373X</identifier><identifier>EISSN: 0032-373X</identifier><identifier>EISSN: 2299-2847</identifier><identifier>DOI: 10.1515/pjs-2015-0046</identifier><identifier>PMID: 26172161</identifier><language>eng</language><publisher>Poland: De Gruyter Open</publisher><subject>center experience ; center volume ; Donor Selection ; donors ; End Stage Liver Disease - surgery ; Female ; Humans ; liver transplantation ; Liver Transplantation - mortality ; Liver Transplantation - statistics & numerical data ; Male ; Middle Aged ; outcomes ; Poland ; Retrospective Studies ; Severity of Illness Index ; survival ; Survival Analysis ; Survival Rate ; Tissue Donors - statistics & numerical data ; Treatment Outcome</subject><ispartof>Polski przeglad chirurgiczny, 2015-05, Vol.87 (5), p.221-230</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2601-6e3d1e02e513bb2ccd308cb4a5c8fb4ef40a4796acf25f867d11113f08921e8f3</citedby><cites>FETCH-LOGICAL-c2601-6e3d1e02e513bb2ccd308cb4a5c8fb4ef40a4796acf25f867d11113f08921e8f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26172161$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Krawczyk, Marek</creatorcontrib><creatorcontrib>Grąt, Michał</creatorcontrib><creatorcontrib>Grąt, Karolina</creatorcontrib><creatorcontrib>Wronka, Karolina</creatorcontrib><creatorcontrib>Krasnodębski, Maciej</creatorcontrib><creatorcontrib>Stypułkowski, Jan</creatorcontrib><creatorcontrib>Masior, Łukasz</creatorcontrib><creatorcontrib>Hołówko, Wacław</creatorcontrib><creatorcontrib>Ligocka, Joanna</creatorcontrib><creatorcontrib>Nyckowski, Paweł</creatorcontrib><creatorcontrib>Wróblewski, Tadeusz</creatorcontrib><creatorcontrib>Paluszkiewicz, Rafał</creatorcontrib><creatorcontrib>Patkowski, Waldemar</creatorcontrib><creatorcontrib>Zieniewicz, Krzysztof</creatorcontrib><creatorcontrib>Pączek, Leszek</creatorcontrib><creatorcontrib>Milkiewicz, Piotr</creatorcontrib><creatorcontrib>Ołdakowska-Jedynak, Urszula</creatorcontrib><creatorcontrib>Najnigier, Bogusław</creatorcontrib><creatorcontrib>Dudek, Krzysztof</creatorcontrib><creatorcontrib>Remiszewski, Piotr</creatorcontrib><creatorcontrib>Grzelak, Ireneusz</creatorcontrib><creatorcontrib>Kornasiewicz, Oskar</creatorcontrib><creatorcontrib>Kotulski, Marcin</creatorcontrib><creatorcontrib>Smoter, Piotr</creatorcontrib><creatorcontrib>Grodzicki, Mariusz</creatorcontrib><creatorcontrib>Korba, Michał</creatorcontrib><creatorcontrib>Kalinowski, Piotr</creatorcontrib><creatorcontrib>Skalski, Michał</creatorcontrib><creatorcontrib>Zając, Krzysztof</creatorcontrib><creatorcontrib>Stankiewicz, Rafał</creatorcontrib><creatorcontrib>Przybysz, Marta</creatorcontrib><creatorcontrib>Cieślak, Bartosz</creatorcontrib><creatorcontrib>Nazarewski, Łukasz</creatorcontrib><creatorcontrib>Nowosad, Małgorzata</creatorcontrib><creatorcontrib>Kobryń, Konrad</creatorcontrib><creatorcontrib>Wasilewicz, Michał</creatorcontrib><creatorcontrib>Raszeja-Wyszomirska, Joanna</creatorcontrib><creatorcontrib>Piwowarska, Jolanta</creatorcontrib><creatorcontrib>Giercuszkiewicz, Dorota</creatorcontrib><creatorcontrib>Sańko-Resmer, Joanna</creatorcontrib><creatorcontrib>Rejowski, Sławomir</creatorcontrib><creatorcontrib>Szydłowska-Jakimiuk, Monika</creatorcontrib><creatorcontrib>Górnicka, Barbara</creatorcontrib><creatorcontrib>Wróblewska-Ziarkiewicz, Bogna</creatorcontrib><creatorcontrib>Mazurkiewicz, Michał</creatorcontrib><creatorcontrib>Niewiński, Grzegorz</creatorcontrib><creatorcontrib>Pawlak, Jacek</creatorcontrib><creatorcontrib>Pacho, Ryszard</creatorcontrib><title>Evolution Of The Results Of 1500 Liver Transplantations Performed In The Department Of General, Transplant And Liver Surgery Medical University Of Warsaw</title><title>Polski przeglad chirurgiczny</title><addtitle>Pol Przegl Chir</addtitle><description><![CDATA[Liver transplantation is a well-established treatment of patients with end-stage liver disease and selected liver tumors. Remarkable progress has been made over the last years concerning nearly all of its aspects.
was to evaluate the evolution of long-term outcomes after liver transplantations performed in the Department of General, Transplant and Liver Surgery (Medical University of Warsaw).
Data of 1500 liver transplantations performed between 1989 and 2014 were retrospectively analyzed. Transplantations were divided into 3 groups: group 1 including first 500 operations, group 2 including subsequent 500, and group 3 comprising the most recent 500. Five year overall and graft survival were set as outcome measures.
Increased number of transplantations performed at the site was associated with increased age of the recipients (p<0.001) and donors (p<0.001), increased rate of male recipients (p<0.001), and increased rate of piggyback operations (p<0.001), and decreased MELD (p<0.001), as well as decreased blood (p=0.006) and plasma (p<0.001) transfusions. Overall survival was 71.6% at 5 years in group 1, 74.5% at 5 years in group 2, and 85% at 2.9 years in group 3 (p=0.008). Improvement of overall survival was particularly observed for primary transplantations (p=0.004). Increased graft survival rates did not reach the level of significance (p=0.136).
Long-term outcomes after liver transplantations performed in the Department of General, Transplant and Liver Surgery are comparable to those achieved in the largest transplant centers worldwide and are continuously improving despite increasing recipient age and wider utilization of organs procured from older donors.]]></description><subject>center experience</subject><subject>center volume</subject><subject>Donor Selection</subject><subject>donors</subject><subject>End Stage Liver Disease - surgery</subject><subject>Female</subject><subject>Humans</subject><subject>liver transplantation</subject><subject>Liver Transplantation - mortality</subject><subject>Liver Transplantation - statistics & numerical data</subject><subject>Male</subject><subject>Middle Aged</subject><subject>outcomes</subject><subject>Poland</subject><subject>Retrospective Studies</subject><subject>Severity of Illness Index</subject><subject>survival</subject><subject>Survival Analysis</subject><subject>Survival 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Joanna</creatorcontrib><creatorcontrib>Piwowarska, Jolanta</creatorcontrib><creatorcontrib>Giercuszkiewicz, Dorota</creatorcontrib><creatorcontrib>Sańko-Resmer, Joanna</creatorcontrib><creatorcontrib>Rejowski, Sławomir</creatorcontrib><creatorcontrib>Szydłowska-Jakimiuk, Monika</creatorcontrib><creatorcontrib>Górnicka, Barbara</creatorcontrib><creatorcontrib>Wróblewska-Ziarkiewicz, Bogna</creatorcontrib><creatorcontrib>Mazurkiewicz, Michał</creatorcontrib><creatorcontrib>Niewiński, Grzegorz</creatorcontrib><creatorcontrib>Pawlak, Jacek</creatorcontrib><creatorcontrib>Pacho, Ryszard</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Polski przeglad chirurgiczny</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Krawczyk, Marek</au><au>Grąt, Michał</au><au>Grąt, Karolina</au><au>Wronka, Karolina</au><au>Krasnodębski, Maciej</au><au>Stypułkowski, Jan</au><au>Masior, Łukasz</au><au>Hołówko, Wacław</au><au>Ligocka, Joanna</au><au>Nyckowski, Paweł</au><au>Wróblewski, Tadeusz</au><au>Paluszkiewicz, Rafał</au><au>Patkowski, Waldemar</au><au>Zieniewicz, Krzysztof</au><au>Pączek, Leszek</au><au>Milkiewicz, Piotr</au><au>Ołdakowska-Jedynak, Urszula</au><au>Najnigier, Bogusław</au><au>Dudek, Krzysztof</au><au>Remiszewski, Piotr</au><au>Grzelak, Ireneusz</au><au>Kornasiewicz, Oskar</au><au>Kotulski, Marcin</au><au>Smoter, Piotr</au><au>Grodzicki, Mariusz</au><au>Korba, Michał</au><au>Kalinowski, Piotr</au><au>Skalski, Michał</au><au>Zając, Krzysztof</au><au>Stankiewicz, Rafał</au><au>Przybysz, Marta</au><au>Cieślak, Bartosz</au><au>Nazarewski, Łukasz</au><au>Nowosad, Małgorzata</au><au>Kobryń, Konrad</au><au>Wasilewicz, Michał</au><au>Raszeja-Wyszomirska, Joanna</au><au>Piwowarska, Jolanta</au><au>Giercuszkiewicz, Dorota</au><au>Sańko-Resmer, Joanna</au><au>Rejowski, Sławomir</au><au>Szydłowska-Jakimiuk, Monika</au><au>Górnicka, Barbara</au><au>Wróblewska-Ziarkiewicz, Bogna</au><au>Mazurkiewicz, Michał</au><au>Niewiński, Grzegorz</au><au>Pawlak, Jacek</au><au>Pacho, Ryszard</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Evolution Of The Results Of 1500 Liver Transplantations Performed In The Department Of General, Transplant And Liver Surgery Medical University Of Warsaw</atitle><jtitle>Polski przeglad chirurgiczny</jtitle><addtitle>Pol Przegl Chir</addtitle><date>2015-05-01</date><risdate>2015</risdate><volume>87</volume><issue>5</issue><spage>221</spage><epage>230</epage><pages>221-230</pages><issn>0032-373X</issn><eissn>0032-373X</eissn><eissn>2299-2847</eissn><abstract><![CDATA[Liver transplantation is a well-established treatment of patients with end-stage liver disease and selected liver tumors. Remarkable progress has been made over the last years concerning nearly all of its aspects.
was to evaluate the evolution of long-term outcomes after liver transplantations performed in the Department of General, Transplant and Liver Surgery (Medical University of Warsaw).
Data of 1500 liver transplantations performed between 1989 and 2014 were retrospectively analyzed. Transplantations were divided into 3 groups: group 1 including first 500 operations, group 2 including subsequent 500, and group 3 comprising the most recent 500. Five year overall and graft survival were set as outcome measures.
Increased number of transplantations performed at the site was associated with increased age of the recipients (p<0.001) and donors (p<0.001), increased rate of male recipients (p<0.001), and increased rate of piggyback operations (p<0.001), and decreased MELD (p<0.001), as well as decreased blood (p=0.006) and plasma (p<0.001) transfusions. Overall survival was 71.6% at 5 years in group 1, 74.5% at 5 years in group 2, and 85% at 2.9 years in group 3 (p=0.008). Improvement of overall survival was particularly observed for primary transplantations (p=0.004). Increased graft survival rates did not reach the level of significance (p=0.136).
Long-term outcomes after liver transplantations performed in the Department of General, Transplant and Liver Surgery are comparable to those achieved in the largest transplant centers worldwide and are continuously improving despite increasing recipient age and wider utilization of organs procured from older donors.]]></abstract><cop>Poland</cop><pub>De Gruyter Open</pub><pmid>26172161</pmid><doi>10.1515/pjs-2015-0046</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0032-373X |
| ispartof | Polski przeglad chirurgiczny, 2015-05, Vol.87 (5), p.221-230 |
| issn | 0032-373X 0032-373X 2299-2847 |
| language | eng |
| recordid | cdi_crossref_primary_10_1515_pjs_2015_0046 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | center experience center volume Donor Selection donors End Stage Liver Disease - surgery Female Humans liver transplantation Liver Transplantation - mortality Liver Transplantation - statistics & numerical data Male Middle Aged outcomes Poland Retrospective Studies Severity of Illness Index survival Survival Analysis Survival Rate Tissue Donors - statistics & numerical data Treatment Outcome |
| title | Evolution Of The Results Of 1500 Liver Transplantations Performed In The Department Of General, Transplant And Liver Surgery Medical University Of Warsaw |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-11T06%3A29%3A51IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-walterdegruyter_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Evolution%20Of%20The%20Results%20Of%201500%20Liver%20Transplantations%20Performed%20In%20The%20Department%20Of%20General,%20Transplant%20And%20Liver%20Surgery%20Medical%20University%20Of%20Warsaw&rft.jtitle=Polski%20przeglad%20chirurgiczny&rft.au=Krawczyk,%20Marek&rft.date=2015-05-01&rft.volume=87&rft.issue=5&rft.spage=221&rft.epage=230&rft.pages=221-230&rft.issn=0032-373X&rft.eissn=0032-373X&rft_id=info:doi/10.1515/pjs-2015-0046&rft_dat=%3Cwalterdegruyter_cross%3E10_1515_pjs_2015_0046875221%3C/walterdegruyter_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/26172161&rfr_iscdi=true |