Imaging of myocardial infarction with thermoacoustic tomography: An ex vivo study
In the present study, we evaluated the feasibility of thermoacoustic tomography (TAT) for imaging of ex vivo mouse hearts with myocardial infarction. A circular scanning TAT system with an unfocused transducer was used to recover the dielectric property distribution of normal andmyocardial infarcted...
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| Veröffentlicht in: | X-Acoustics: imaging and sensing 2015-08, Vol.1 (1) |
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| creator | Weizhi, Qi Wei, Cai Xi, Lu Jian, Rong Lin, Huang |
| description | In the present study, we evaluated the feasibility
of thermoacoustic tomography (TAT) for imaging of ex
vivo mouse hearts with myocardial infarction. A circular
scanning TAT system with an unfocused transducer was
used to recover the dielectric property distribution of normal
andmyocardial infarcted mouse heart tissues. The applicability
of this myocardial infarction imaging system
was validated using a model of myocardial infarction in
two Sprague-Dawley rats and verified through comparison
with magnetic resonance imaging (MRI). TAT results not
only indicated the location and ischemia and the extent of
myocardial ischemia (MI), but also showed good imaging
contrast between infarcted and normal myocardium without
the use of contrast agent. The experimental results suggest
that TAT may provide a unique opportunity to enable
real-time precision imaging to determine the site of injury
intraoperatively |
| doi_str_mv | 10.1515/phto-2015-0003 |
| format | Article |
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of thermoacoustic tomography (TAT) for imaging of ex
vivo mouse hearts with myocardial infarction. A circular
scanning TAT system with an unfocused transducer was
used to recover the dielectric property distribution of normal
andmyocardial infarcted mouse heart tissues. The applicability
of this myocardial infarction imaging system
was validated using a model of myocardial infarction in
two Sprague-Dawley rats and verified through comparison
with magnetic resonance imaging (MRI). TAT results not
only indicated the location and ischemia and the extent of
myocardial ischemia (MI), but also showed good imaging
contrast between infarcted and normal myocardium without
the use of contrast agent. The experimental results suggest
that TAT may provide a unique opportunity to enable
real-time precision imaging to determine the site of injury
intraoperatively</description><identifier>ISSN: 2353-0634</identifier><identifier>EISSN: 2353-0634</identifier><identifier>DOI: 10.1515/phto-2015-0003</identifier><language>eng</language><publisher>De Gruyter Open</publisher><subject>MRI ; Myocardial ischemia ; Thermoacoustic tomography</subject><ispartof>X-Acoustics: imaging and sensing, 2015-08, Vol.1 (1)</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c881-e688fddfe76e49792e1ac10843e4e0d9314408e4cb9eef548c277696d87de12f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids></links><search><creatorcontrib>Weizhi, Qi</creatorcontrib><creatorcontrib>Wei, Cai</creatorcontrib><creatorcontrib>Xi, Lu</creatorcontrib><creatorcontrib>Jian, Rong</creatorcontrib><creatorcontrib>Lin, Huang</creatorcontrib><title>Imaging of myocardial infarction with thermoacoustic tomography: An ex vivo study</title><title>X-Acoustics: imaging and sensing</title><description>In the present study, we evaluated the feasibility
of thermoacoustic tomography (TAT) for imaging of ex
vivo mouse hearts with myocardial infarction. A circular
scanning TAT system with an unfocused transducer was
used to recover the dielectric property distribution of normal
andmyocardial infarcted mouse heart tissues. The applicability
of this myocardial infarction imaging system
was validated using a model of myocardial infarction in
two Sprague-Dawley rats and verified through comparison
with magnetic resonance imaging (MRI). TAT results not
only indicated the location and ischemia and the extent of
myocardial ischemia (MI), but also showed good imaging
contrast between infarcted and normal myocardium without
the use of contrast agent. The experimental results suggest
that TAT may provide a unique opportunity to enable
real-time precision imaging to determine the site of injury
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of thermoacoustic tomography (TAT) for imaging of ex
vivo mouse hearts with myocardial infarction. A circular
scanning TAT system with an unfocused transducer was
used to recover the dielectric property distribution of normal
andmyocardial infarcted mouse heart tissues. The applicability
of this myocardial infarction imaging system
was validated using a model of myocardial infarction in
two Sprague-Dawley rats and verified through comparison
with magnetic resonance imaging (MRI). TAT results not
only indicated the location and ischemia and the extent of
myocardial ischemia (MI), but also showed good imaging
contrast between infarcted and normal myocardium without
the use of contrast agent. The experimental results suggest
that TAT may provide a unique opportunity to enable
real-time precision imaging to determine the site of injury
intraoperatively</abstract><pub>De Gruyter Open</pub><doi>10.1515/phto-2015-0003</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | X-Acoustics: imaging and sensing, 2015-08, Vol.1 (1) |
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| language | eng |
| recordid | cdi_crossref_primary_10_1515_phto_2015_0003 |
| source | Portico (Triggered Content) Open Access |
| subjects | MRI Myocardial ischemia Thermoacoustic tomography |
| title | Imaging of myocardial infarction with thermoacoustic tomography: An ex vivo study |
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