Accurate Microsatellite Typing and Inter-study Comparison: Pitfalls and Solutions Using Interferon-γ (IFNG) and Natural Resistance-associated Mocrophage Protein 2 (NRAMP2) Genes as Examples
Microsatellite typing is frequently used in disease diagnosis and in genetic association studies. Inter-study consistency and comparability is essential in both applications. In this study, we show that the interlaboratory comparison of microsatellite sizes is often discrepant and misleading. This i...
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Veröffentlicht in: | Clinical chemistry and laboratory medicine 2002-09, Vol.40 (9), p.926-929 |
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Format: | Artikel |
Sprache: | eng |
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