State-of-the-art of 3D cultures (organs-on-a-chip) in safety testing and pathophysiology

Integrated approaches using different in vitro methods in combination with bioinformatics can (i) increase the success rate and speed of drug development; (ii) improve the accuracy of toxicological risk assessment; and (iii) increase our understanding of disease. Three-dimensional (3D) cell culture...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	ALTEX 2014, Vol.31 (4), p.441-477
Hauptverfasser:	Alépée, Natalie, Bahinski, Anthony, Daneshian, Mardas, De Wever, Bart, Fritsche, Ellen, Goldberg, Alan, Hansmann, Jan, Hartung, Thomas, Haycock, John, Hogberg, Helena, Hoelting, Lisa, Kelm, Jens M, Kadereit, Suzanne, McVey, Emily, Landsiedel, Robert, Leist, Marcel, Lübberstedt, Marc, Noor, Fozia, Pellevoisin, Christian, Petersohn, Dirk, Pfannenbecker, Uwe, Reisinger, Kerstin, Ramirez, Tzutzuy, Rothen-Rutishauser, Barbara, Schäfer-Korting, Monika, Zeilinger, Katrin, Zurich, Marie-Gabriele
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Testing Alternatives - methods Animals Biological Assay - instrumentation Biological Assay - methods Cell Culture Techniques - instrumentation Cell Culture Techniques - methods Lab-On-A-Chip Devices Models, Biological
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!