Novel Triazolo[4,3-a]pyrazines as Potential MmpL3 Inhibitors: Design, Synthesis, Antitubercular Evaluation and Molecular Docking Studies

A series of biologically active novel triazolo[4,3-a]pyrazines (5a-f) were synthesized and characterized by spectroscopic techniques. The synthesized compounds 5a-f were evaluated for their in vitro anti-tubercular (anti-TB) activity against drug-sensitive Mtb H37Rv (ATCC 27294) strain as well as tw...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Asian journal of chemistry 2024-11, Vol.36 (12), p.2817-2826
Hauptverfasser:	Kshirsagar, Jayashree, Chandane, Wilson, Hiwarale, Dipak, Naik, Nitin, Sonawane, Kailas, Rashinkar, Gajanan, Salunkhe, Rajashri, Shirke, Sunita
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!