Aedes aegypti mosquito saliva ameliorates acetaminophen-induced liver injury in mice

Acetaminophen (N-acetyl-p-aminophenol, APAP) overdose is the most common cause of drug-induced liver injury (DILI). Although the primary hepatic damage is induced by APAP-derived toxic intermediates resulting from cytochrome P450 metabolism, immune components also play an important role in DILI path...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2021-02, Vol.16 (2), p.e0245788
Hauptverfasser:	Assis, Josiane B, Cogliati, Bruno, Esteves, Eliane, Capurro, Margareth L, Fonseca, Denise M, Sá-Nunes, Anderson
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetaminophen Adverse events Aedes aegypti Aminophenol Analgesics Animal models Antibodies Biology and Life Sciences Complications and side effects Data analysis Emergency medical care Emergency medical services Funding Health aspects Immune system Immunomodulation Injuries Liver Liver diseases Medicine and Health Sciences Methodology Mosquitoes p-Aminophenol Paracetamol Prevention Protease inhibitors Proteinase inhibitors Proteins Public health Research and Analysis Methods Saliva Salivary glands secretions Sodium chloride Visualization
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!