The Usefulness of Calyculin A for Cytogenetic Prenatal Diagnosis

An increased number of chromosome plates can be obtained by use of calyculin A (CLA). CLA is an inhibitor of protein phosphatases (type 1 and type 2A serine/threonine). Inactivation of these phosphatases leads to premature chromosome condensation (PCC) in all phases of the cell cycle; thus, it is po...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	The journal of histochemistry and cytochemistry 2005-03, Vol.53 (3), p.391-394
Hauptverfasser:	Srebniak, Malgorzata I, Trapp, Gizela G, Wawrzkiewicz, Angelika K, Kazmierczak, Wojciech, Wiczkowski, Andrzej K
Format:	Artikel
Sprache:	eng
Schlagworte:	Amniotic Fluid - cytology Cell Division Cells, Cultured Centromere - ultrastructure Chromosome Banding Chromosome Breakage Chromosomes, Human - ultrastructure Cytogenetic Analysis G2 Phase Humans Karyotyping Oxazoles Phosphoprotein Phosphatases - antagonists & inhibitors Prenatal Diagnosis - methods
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!