Beam-angle-scanning surface plasmon resonance sensor for rapid, high-precision sensing of refractive index and bio-molecules

Surface plasmon resonance (SPR) sensors are powerful tools for optical sensing of refractive index (RI) and bio-molecules due to their high sensitivity. In this article, we demonstrate a beam-angle-scanning SPR system using a combined galvanometer mirror and relay lens optics. Use of a photodetector...

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Veröffentlicht in:Optics continuum 2022-03, Vol.1 (3), p.565
Hauptverfasser: Koresawa, Hidenori, Seki, Kota, Hase, Eiji, Tokizane, Yu, Minamikawa, Takeo, Yano, Taka-Aki, Kajisa, Taira, Yasui, Takeshi
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container_issue 3
container_start_page 565
container_title Optics continuum
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creator Koresawa, Hidenori
Seki, Kota
Hase, Eiji
Tokizane, Yu
Minamikawa, Takeo
Yano, Taka-Aki
Kajisa, Taira
Yasui, Takeshi
description Surface plasmon resonance (SPR) sensors are powerful tools for optical sensing of refractive index (RI) and bio-molecules due to their high sensitivity. In this article, we demonstrate a beam-angle-scanning SPR system using a combined galvanometer mirror and relay lens optics. Use of a photodetector in the galvanometer mirror scanning of the incident beam angle enables both high precision and rapid data acquisition. RI resolution of 2.306×10 −5 refractive index unit (RIU) and RI accuracy of 8.984×10 −5 RIU were achieved at a data acquisition rate of 100 Hz. Furthermore, we performed real-time monitoring of the avidin-biotin antigen-antibody reaction. The results show the high potential of this beam-angle-scanning SPR system.
doi_str_mv 10.1364/OPTCON.451947
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title Beam-angle-scanning surface plasmon resonance sensor for rapid, high-precision sensing of refractive index and bio-molecules
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