Morphine-Induced Muscle Rigidity in a Term Neonate

Objective: To describe a potentially fatal adverse drug event after administration of morphine to a term neonate. Case Summary: A 2-day-old term neonate experienced generalized muscle rigidity and laryngeal spasm resulting in acute respiratory failure on 2 separate occasions after morphine administr...

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Veröffentlicht in:	The Annals of pharmacotherapy 2009-10, Vol.43 (10), p.1724-1726
Hauptverfasser:	van der Lee, Robin, Ceelie, Ilse, de Wildt, Saskia N
Format:	Artikel
Sprache:	eng
Schlagworte:	Analgesics, Opioid - adverse effects Analgesics, Opioid - therapeutic use Biological and medical sciences Clinical trial. Drug monitoring Drug toxicity and drugs side effects treatment Fentanyl - adverse effects Fentanyl - therapeutic use General pharmacology Humans Infant, Newborn Male Medical sciences Miscellaneous (drug allergy, mutagens, teratogens...) Morphine - adverse effects Morphine - therapeutic use Muscle Rigidity - chemically induced Naloxone - therapeutic use Narcotic Antagonists - therapeutic use Pharmacology. Drug treatments Propofol - therapeutic use
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