Pharmacokinetic Interaction Between Everolimus and Antifungal Triazoles in a Liver Transplant Patient

Objective: TO describe the management of a pharmacokinetic interaction between azole antifungals (fluconazole and voriconazole) and everolimus in a patient who underwent an orthotopic liver transplant. Case Summary: A 65-year-old male who received an orthotopic liver transplant experienced an iatrog...

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Veröffentlicht in:	The Annals of pharmacotherapy 2008-11, Vol.42 (11), p.1711-1716
Hauptverfasser:	Pea, Federico, Baccarani, Umberto, Tavio, Marcello, Cojutti, Piergiorgio, Adani, Gian Luigi, Londero, Angela, Baraldo, Massimo, Franceschi, Loretta, Furlanut, Mario, Viale, Pierluigi
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antifungal Agents - pharmacokinetics Antifungal Agents - therapeutic use Aspergillosis - drug therapy Biological and medical sciences Drug Interactions Everolimus Fatal Outcome Fluconazole - pharmacokinetics Fluconazole - therapeutic use Humans Immunosuppressive Agents - blood Immunosuppressive Agents - pharmacokinetics Immunosuppressive Agents - therapeutic use Liver Transplantation - adverse effects Male Medical sciences Pharmacology. Drug treatments Pyrimidines - pharmacokinetics Pyrimidines - therapeutic use Sirolimus - analogs & derivatives Sirolimus - blood Sirolimus - pharmacokinetics Sirolimus - therapeutic use Triazoles - pharmacokinetics Triazoles - therapeutic use Voriconazole
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