Use of intravenous valproate in three pediatric patients with nonconvulsive or convulsive status epilepticus

OBJECTIVE: To report the pharmacokinetics of intravenous valproate (VPA) in children with generalized convulsive status epilepticus (GCSE) or nonconvulsive status epilepticus (NCSE). To provide loading and maintenance dosing for patients with hepatic induction secondary to concurrent anticonvulsants...

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Veröffentlicht in:	The Annals of pharmacotherapy 1999-05, Vol.33 (5), p.579-584
Hauptverfasser:	Hovinga, CA, Chicella, MF, Rose, DF, Eades, SK, Dalton, JT, Phelps, SJ
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticonvulsants - administration & dosage Anticonvulsants - pharmacokinetics Anticonvulsants. Antiepileptics. Antiparkinson agents Biological and medical sciences Child Child, Preschool Drug Administration Schedule Drug Interactions Enzyme Induction Female Humans Infusions, Intravenous Male Medical sciences Neuropharmacology Pentobarbital - pharmacokinetics Pharmacology. Drug treatments Seizures - drug therapy Status Epilepticus - drug therapy Valproic Acid - administration & dosage Valproic Acid - pharmacokinetics
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