The canals of hering might represent a target of methotrexate hepatic toxicity

Methotrexate treatment for psoriasis is known to cause hepatic fibrosis in some patients, which might progress to cirrhosis. The fine, radiating, fibrous septa developing in this setting have a distribution that is reminiscent of the location of the canals of Hering (coH). To assess the possibility...

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Veröffentlicht in:	American journal of clinical pathology 2004-03, Vol.121 (3), p.324-329
Hauptverfasser:	HYTIROGLOU, Prodromos, TOBIAS, Hillel, SAXENA, Romil, ABRAMIDOU, Martha, PAPADIMITRIOU, Constantine S, THEISE, Neil D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biological and medical sciences Female Humans Immunosuppressive Agents - toxicity Investigative techniques, diagnostic techniques (general aspects) Liver - drug effects Liver - pathology Male Medical sciences Methotrexate - toxicity Middle Aged Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Psoriasis - drug therapy
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