Identification and characterization of spontaneous AA amyloidosis in CD-1 mice used in toxicity studies: implications of SAA1 and SAA2 copy number variations

Amyloidosis is characterized by the extracellular deposition of insoluble protein fibrils that cause cellular damage and dysfunction in organs and tissues. Multiple types of amyloidosis and their causative precursor proteins have been identified in humans and animals. In toxicological studies, a hig...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of Toxicologic Pathology 2024, pp.2024-0070
Hauptverfasser:	MIZUKAWA, Mao, TANAKA, Kohei, KASHIMURA, Akane, UCHIDA, Yu, SHIGA, Takanori, AIHARA, Naoyuki, KAMIE, Junichi
Format:	Artikel
Sprache:	eng
Schlagworte:	AA amyloidosis amyloidosis CD-1 mice copy number variation (CNVs) Original serum amyloid A (SAA)
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!