Technical Report: Application of Rat Precision-cut Liver Slices for Toxicity Assessment In Vitro

The usefulness of precision-cut liver slices for toxicological evaluation in vitro was confirmed with a representative hepatotoxic agent acetaminophen. Liver slices obtained from normal and in vivo phenobarbital-treated rats were incubated with 0, 1.25, 2.5, 5, and 10 mM of acetaminophen for 24 hour...

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Veröffentlicht in:Journal of Toxicologic Pathology 1999, Vol.12(2), pp.71-71
Hauptverfasser: Kitamura, Kazuyuki, Tokito, Yasuhiro, Dekura, Eriha, Kawai, Yoshiaki
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Sprache:eng
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