Toxic effects of cisplatin alone and in combination with gentamicin in stria vascularis of guinea pigs

The toxic effects on the stria vascularis of treatment with cisplatin alone and combined with the aminoglycoside antibiotic, gentamicin, were studied in guinea pigs. The toxicity induced in albino and pigmented guinea pigs was investigated morphologically with light and transmission electron microsc...

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Veröffentlicht in:	The Laryngoscope 1991-07, Vol.101 (7), p.709-716
Hauptverfasser:	Kohn, Sarah, Nir, Izhak, Fradis, Milo, Podoshin, Ludwig, David, Yaacov Ben, Zidan, Jamal, Robinson, Eliezer
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cisplatin - toxicity Drug Combinations Evoked Potentials, Auditory, Brain Stem Gentamicins - toxicity Guinea Pigs Hearing Disorders - chemically induced Hearing Loss, Bilateral - chemically induced Microscopy, Electron Microscopy, Electron, Scanning Stria Vascularis - drug effects Stria Vascularis - ultrastructure
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