Cisplatin ototoxicity in guinea pigs with special reference to toxic effects in the stria vascularis

The toxic effects of cisplatin (cis‐diamminedichloroplatinum [II]) on the organ of Corti are well established. Few and conflicting data on this drug's effects on the stria vascularis exist. The present study presents animal experiments on the toxic effects of cisplatin in the stria vascularis a...

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Veröffentlicht in:	The Laryngoscope 1988-08, Vol.98 (8), p.865-871
Hauptverfasser:	Kohn, Sarah, Pratt, Hillel, Robinson, Eliezer, Nir, Izhak, Fradis, Milo, Podoshin, Ludwig, Zidan, Jamal
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Audiometry, Evoked Response Biological and medical sciences Cisplatin - toxicity Cochlea - drug effects Drug toxicity and drugs side effects treatment Evoked Potentials, Auditory - drug effects Guinea Pigs Labyrinth Diseases - chemically induced Medical sciences Microscopy, Electron Miscellaneous (drug allergy, mutagens, teratogens...) Organ of Corti - drug effects Pharmacology. Drug treatments Stria Vascularis - drug effects
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