A review of existing neonatal hyperbilirubinemia guidelines in Indonesia [version 1; peer review: 2 approved with reservations]
Background: Neonatal hyperbilirubinemia is one of the most common conditions for neonate inpatients. Indonesia faces a major challenge in which different guidelines regarding the management of this condition were present. This study aimed to compare the existing guidelines regarding prevention, diag...
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creator | Sampurna, Mahendra Tri Arif Liem, Kian Djien Pratama, Danny Chandra Oktaviana, Novita Putra, Achmad Januar Er Zakiyah, Rahmi Visuddho, Visuddho Etika, Risa Handayani, Kartika Dharma Utomo, Martono Tri Angelica, Dina Ayuningtyas, Wurry Hendrarto, Toto Wisnu Rohsiswatmo, Rinawati Wandita, Setya Kaban, Risma Karina Ahmad, Jordy Maulana |
description | Background: Neonatal
hyperbilirubinemia is one of the most common conditions for neonate inpatients. Indonesia faces a major challenge in which different guidelines regarding the management of this condition were present. This study aimed to compare the existing guidelines regarding prevention, diagnosis, treatment and monitoring in order to create the best recommendation for a new hyperbilirubinemia guideline in Indonesia.
Methods: Through an earlier survey regarding adherence to the neonatal hyperbilirubinemia guideline, we identified that three main guidelines are being used in Indonesia. These were developed by the Indonesian Pediatric Society (IPS), the Ministry of Health (MoH), and World Health Organization (WHO). In this study, we compared factors such as prevention, monitoring, methods for identifying, risk factors in the development of neonatal jaundice, risk factors that increase brain damage, and intervention treatment threshold in the existing guidelines to determine the best recommendations for a new guideline.
Results: The MoH and WHO guidelines allow screening and treatment of hyperbilirubinemia based on visual examination (VE) only. Compared with the MoH and WHO guidelines, risk assessment is comprehensively discussed in the IPS guideline. The MoH guideline recommends further examination of an icteric baby to ensure that the mother has enough milk without measuring the bilirubin level. The MoH guideline recommends referring the baby when it looks yellow on the soles and palms. The WHO and IPS guidelines recommend combining VE with an objective measurement of transcutaneous or serum bilirubin. The threshold to begin phototherapy in the WHO guideline is lower than the IPS guideline while the exchange transfusion threshold in both guidelines are comparably equal.
Conclusions: The MoH guideline is outdated. MoH and IPS guidelines are causing differences in approaches to the management hyperbilirubinemia. A new, uniform guideline is required. |
doi_str_mv | 10.12688/f1000research.110550.1 |
format | Article |
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hyperbilirubinemia is one of the most common conditions for neonate inpatients. Indonesia faces a major challenge in which different guidelines regarding the management of this condition were present. This study aimed to compare the existing guidelines regarding prevention, diagnosis, treatment and monitoring in order to create the best recommendation for a new hyperbilirubinemia guideline in Indonesia.
Methods: Through an earlier survey regarding adherence to the neonatal hyperbilirubinemia guideline, we identified that three main guidelines are being used in Indonesia. These were developed by the Indonesian Pediatric Society (IPS), the Ministry of Health (MoH), and World Health Organization (WHO). In this study, we compared factors such as prevention, monitoring, methods for identifying, risk factors in the development of neonatal jaundice, risk factors that increase brain damage, and intervention treatment threshold in the existing guidelines to determine the best recommendations for a new guideline.
Results: The MoH and WHO guidelines allow screening and treatment of hyperbilirubinemia based on visual examination (VE) only. Compared with the MoH and WHO guidelines, risk assessment is comprehensively discussed in the IPS guideline. The MoH guideline recommends further examination of an icteric baby to ensure that the mother has enough milk without measuring the bilirubin level. The MoH guideline recommends referring the baby when it looks yellow on the soles and palms. The WHO and IPS guidelines recommend combining VE with an objective measurement of transcutaneous or serum bilirubin. The threshold to begin phototherapy in the WHO guideline is lower than the IPS guideline while the exchange transfusion threshold in both guidelines are comparably equal.
Conclusions: The MoH guideline is outdated. MoH and IPS guidelines are causing differences in approaches to the management hyperbilirubinemia. A new, uniform guideline is required.</description><identifier>ISSN: 2046-1402</identifier><identifier>EISSN: 2046-1402</identifier><identifier>DOI: 10.12688/f1000research.110550.1</identifier><language>eng</language><ispartof>F1000 research, 2022, Vol.11, p.1534</ispartof><rights>Copyright: © 2022 Sampurna MTA et al.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2731-5f0f6d718883fca340cf86f9d58cf574d018717fc4e823ce1083cef6afa62033</citedby><cites>FETCH-LOGICAL-c2731-5f0f6d718883fca340cf86f9d58cf574d018717fc4e823ce1083cef6afa62033</cites><orcidid>0000-0001-9987-9104 ; 0000-0002-6780-6207 ; 0000-0002-7529-8142 ; 0000-0002-7150-0753</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,861,4010,27904,27905,27906</link.rule.ids></links><search><creatorcontrib>Sampurna, Mahendra Tri Arif</creatorcontrib><creatorcontrib>Liem, Kian Djien</creatorcontrib><creatorcontrib>Pratama, Danny Chandra</creatorcontrib><creatorcontrib>Oktaviana, Novita</creatorcontrib><creatorcontrib>Putra, Achmad Januar Er</creatorcontrib><creatorcontrib>Zakiyah, Rahmi</creatorcontrib><creatorcontrib>Visuddho, Visuddho</creatorcontrib><creatorcontrib>Etika, Risa</creatorcontrib><creatorcontrib>Handayani, Kartika Dharma</creatorcontrib><creatorcontrib>Utomo, Martono Tri</creatorcontrib><creatorcontrib>Angelica, Dina</creatorcontrib><creatorcontrib>Ayuningtyas, Wurry</creatorcontrib><creatorcontrib>Hendrarto, Toto Wisnu</creatorcontrib><creatorcontrib>Rohsiswatmo, Rinawati</creatorcontrib><creatorcontrib>Wandita, Setya</creatorcontrib><creatorcontrib>Kaban, Risma Karina</creatorcontrib><creatorcontrib>Ahmad, Jordy Maulana</creatorcontrib><title>A review of existing neonatal hyperbilirubinemia guidelines in Indonesia [version 1; peer review: 2 approved with reservations]</title><title>F1000 research</title><description>Background: Neonatal
hyperbilirubinemia is one of the most common conditions for neonate inpatients. Indonesia faces a major challenge in which different guidelines regarding the management of this condition were present. This study aimed to compare the existing guidelines regarding prevention, diagnosis, treatment and monitoring in order to create the best recommendation for a new hyperbilirubinemia guideline in Indonesia.
Methods: Through an earlier survey regarding adherence to the neonatal hyperbilirubinemia guideline, we identified that three main guidelines are being used in Indonesia. These were developed by the Indonesian Pediatric Society (IPS), the Ministry of Health (MoH), and World Health Organization (WHO). In this study, we compared factors such as prevention, monitoring, methods for identifying, risk factors in the development of neonatal jaundice, risk factors that increase brain damage, and intervention treatment threshold in the existing guidelines to determine the best recommendations for a new guideline.
Results: The MoH and WHO guidelines allow screening and treatment of hyperbilirubinemia based on visual examination (VE) only. Compared with the MoH and WHO guidelines, risk assessment is comprehensively discussed in the IPS guideline. The MoH guideline recommends further examination of an icteric baby to ensure that the mother has enough milk without measuring the bilirubin level. The MoH guideline recommends referring the baby when it looks yellow on the soles and palms. The WHO and IPS guidelines recommend combining VE with an objective measurement of transcutaneous or serum bilirubin. The threshold to begin phototherapy in the WHO guideline is lower than the IPS guideline while the exchange transfusion threshold in both guidelines are comparably equal.
Conclusions: The MoH guideline is outdated. MoH and IPS guidelines are causing differences in approaches to the management hyperbilirubinemia. A new, uniform guideline is required.</description><issn>2046-1402</issn><issn>2046-1402</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNqFUMtOwzAQtBBIVKXfgH8gxY88XHqqKh6VKnHpDSHLddatUepEdprSE7-OSyoBJy67s7szo9UgdEvJmLJciDtDCSEeAiivt2NKSZbF0wUaMJLmCU0Ju_yFr9EohPeoIJMJz1kxQJ8z7KGzcMC1wfBhQ2vdBjuonWpVhbfHBvzaVtbv19bBziq82dsSqjgEbB1euLKOMO5fO_DB1g7TKW4A_Nn3HjOsmsbXHZT4YNstPn3rO9VGbni7QVdGVQFG5z5Eq8eH1fw5Wb48LeazZaJZwWmSGWLysqBCCG604inRRuRmUmZCm6xIS0JFQQujUxCMa6BExGpyZVTOCOdDVPS22tcheDCy8Xan_FFSIr-TlH-SlH2SkkbltFcapfdVezyx5A_tH_UXGZN--Q</recordid><startdate>2022</startdate><enddate>2022</enddate><creator>Sampurna, Mahendra Tri Arif</creator><creator>Liem, Kian Djien</creator><creator>Pratama, Danny Chandra</creator><creator>Oktaviana, Novita</creator><creator>Putra, Achmad Januar Er</creator><creator>Zakiyah, Rahmi</creator><creator>Visuddho, Visuddho</creator><creator>Etika, Risa</creator><creator>Handayani, Kartika Dharma</creator><creator>Utomo, Martono Tri</creator><creator>Angelica, Dina</creator><creator>Ayuningtyas, Wurry</creator><creator>Hendrarto, Toto Wisnu</creator><creator>Rohsiswatmo, Rinawati</creator><creator>Wandita, Setya</creator><creator>Kaban, Risma Karina</creator><creator>Ahmad, Jordy Maulana</creator><scope>C-E</scope><scope>CH4</scope><scope>AAYXX</scope><scope>CITATION</scope><orcidid>https://orcid.org/0000-0001-9987-9104</orcidid><orcidid>https://orcid.org/0000-0002-6780-6207</orcidid><orcidid>https://orcid.org/0000-0002-7529-8142</orcidid><orcidid>https://orcid.org/0000-0002-7150-0753</orcidid></search><sort><creationdate>2022</creationdate><title>A review of existing neonatal hyperbilirubinemia guidelines in Indonesia [version 1; peer review: 2 approved with reservations]</title><author>Sampurna, Mahendra Tri Arif ; Liem, Kian Djien ; Pratama, Danny Chandra ; Oktaviana, Novita ; Putra, Achmad Januar Er ; Zakiyah, Rahmi ; Visuddho, Visuddho ; Etika, Risa ; Handayani, Kartika Dharma ; Utomo, Martono Tri ; Angelica, Dina ; Ayuningtyas, Wurry ; Hendrarto, Toto Wisnu ; Rohsiswatmo, Rinawati ; Wandita, Setya ; Kaban, Risma Karina ; Ahmad, Jordy Maulana</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2731-5f0f6d718883fca340cf86f9d58cf574d018717fc4e823ce1083cef6afa62033</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sampurna, Mahendra Tri Arif</creatorcontrib><creatorcontrib>Liem, Kian Djien</creatorcontrib><creatorcontrib>Pratama, Danny Chandra</creatorcontrib><creatorcontrib>Oktaviana, Novita</creatorcontrib><creatorcontrib>Putra, Achmad Januar Er</creatorcontrib><creatorcontrib>Zakiyah, Rahmi</creatorcontrib><creatorcontrib>Visuddho, Visuddho</creatorcontrib><creatorcontrib>Etika, Risa</creatorcontrib><creatorcontrib>Handayani, Kartika Dharma</creatorcontrib><creatorcontrib>Utomo, Martono Tri</creatorcontrib><creatorcontrib>Angelica, Dina</creatorcontrib><creatorcontrib>Ayuningtyas, Wurry</creatorcontrib><creatorcontrib>Hendrarto, Toto Wisnu</creatorcontrib><creatorcontrib>Rohsiswatmo, Rinawati</creatorcontrib><creatorcontrib>Wandita, Setya</creatorcontrib><creatorcontrib>Kaban, Risma Karina</creatorcontrib><creatorcontrib>Ahmad, Jordy Maulana</creatorcontrib><collection>F1000Research</collection><collection>Faculty of 1000</collection><collection>CrossRef</collection><jtitle>F1000 research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sampurna, Mahendra Tri Arif</au><au>Liem, Kian Djien</au><au>Pratama, Danny Chandra</au><au>Oktaviana, Novita</au><au>Putra, Achmad Januar Er</au><au>Zakiyah, Rahmi</au><au>Visuddho, Visuddho</au><au>Etika, Risa</au><au>Handayani, Kartika Dharma</au><au>Utomo, Martono Tri</au><au>Angelica, Dina</au><au>Ayuningtyas, Wurry</au><au>Hendrarto, Toto Wisnu</au><au>Rohsiswatmo, Rinawati</au><au>Wandita, Setya</au><au>Kaban, Risma Karina</au><au>Ahmad, Jordy Maulana</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A review of existing neonatal hyperbilirubinemia guidelines in Indonesia [version 1; peer review: 2 approved with reservations]</atitle><jtitle>F1000 research</jtitle><date>2022</date><risdate>2022</risdate><volume>11</volume><spage>1534</spage><pages>1534-</pages><issn>2046-1402</issn><eissn>2046-1402</eissn><abstract>Background: Neonatal
hyperbilirubinemia is one of the most common conditions for neonate inpatients. Indonesia faces a major challenge in which different guidelines regarding the management of this condition were present. This study aimed to compare the existing guidelines regarding prevention, diagnosis, treatment and monitoring in order to create the best recommendation for a new hyperbilirubinemia guideline in Indonesia.
Methods: Through an earlier survey regarding adherence to the neonatal hyperbilirubinemia guideline, we identified that three main guidelines are being used in Indonesia. These were developed by the Indonesian Pediatric Society (IPS), the Ministry of Health (MoH), and World Health Organization (WHO). In this study, we compared factors such as prevention, monitoring, methods for identifying, risk factors in the development of neonatal jaundice, risk factors that increase brain damage, and intervention treatment threshold in the existing guidelines to determine the best recommendations for a new guideline.
Results: The MoH and WHO guidelines allow screening and treatment of hyperbilirubinemia based on visual examination (VE) only. Compared with the MoH and WHO guidelines, risk assessment is comprehensively discussed in the IPS guideline. The MoH guideline recommends further examination of an icteric baby to ensure that the mother has enough milk without measuring the bilirubin level. The MoH guideline recommends referring the baby when it looks yellow on the soles and palms. The WHO and IPS guidelines recommend combining VE with an objective measurement of transcutaneous or serum bilirubin. The threshold to begin phototherapy in the WHO guideline is lower than the IPS guideline while the exchange transfusion threshold in both guidelines are comparably equal.
Conclusions: The MoH guideline is outdated. MoH and IPS guidelines are causing differences in approaches to the management hyperbilirubinemia. A new, uniform guideline is required.</abstract><doi>10.12688/f1000research.110550.1</doi><orcidid>https://orcid.org/0000-0001-9987-9104</orcidid><orcidid>https://orcid.org/0000-0002-6780-6207</orcidid><orcidid>https://orcid.org/0000-0002-7529-8142</orcidid><orcidid>https://orcid.org/0000-0002-7150-0753</orcidid><oa>free_for_read</oa></addata></record> |
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title | A review of existing neonatal hyperbilirubinemia guidelines in Indonesia [version 1; peer review: 2 approved with reservations] |
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