Fatal Disseminated Kaposi's Sarcoma in Two Patients with Human Immunodeficiency Virus (HIV) InfectionFatal Disseminated Kaposi's Sarcoma in Two Patients with Human Immunodeficiency Virus (HIV) Infection
BACKGROUND Kaposi's sarcoma (KS) is a common condition in patients with human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS). In these patients, the occurrence of KS is reduced by treatment with highly active antiretroviral therapy (HAART). Fatal and dissem...
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| Veröffentlicht in: | The American journal of case reports 2018-07, Vol.19, p.868-874 |
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| container_title | The American journal of case reports |
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| creator | Fardin, Rafaela Barbirato Leite, Luiz Arhur Calheiros Bezerra, Luanna Mayara Dos Santos Alves, Priscilla Maris Pereira Dos Santos, Layanne Lima Salvá, Marília de Andrade Rezende Filho, Antônio Luiz Soares Moura Lima, Gilberto Salustiano Matos, Juliana de Amorim Ferreira, Sônia Maria Soares Costa, Ducy Lily Joazeiro de Farias |
| description | BACKGROUND Kaposi's sarcoma (KS) is a common condition in patients with human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS). In these patients, the occurrence of KS is reduced by treatment with highly active antiretroviral therapy (HAART). Fatal and disseminated KS is presented in two patients with HIV/AIDS. CASE REPORT A 25-year-old man and a 30-year-old man with HIV/AIDS presented with KS affecting the skin, oral cavity, gastrointestinal tract, liver, lungs, kidneys, adrenal glands, and bone. Both patients had a rapidly deteriorating clinical course associated with a low CD4 count and developed respiratory failure and death. CONCLUSIONS Fatal disseminated KS is associated with severe immunosuppression due to with a low CD4 count. The presentation of these two cases highlights the potentially aggressive clinical course of KS in patients with HIV/AIDS and reinforces the need for early diagnosis and rapid treatment with HAART. |
| doi_str_mv | 10.12659/AJCR.910004 |
| format | Article |
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In these patients, the occurrence of KS is reduced by treatment with highly active antiretroviral therapy (HAART). Fatal and disseminated KS is presented in two patients with HIV/AIDS. CASE REPORT A 25-year-old man and a 30-year-old man with HIV/AIDS presented with KS affecting the skin, oral cavity, gastrointestinal tract, liver, lungs, kidneys, adrenal glands, and bone. Both patients had a rapidly deteriorating clinical course associated with a low CD4 count and developed respiratory failure and death. CONCLUSIONS Fatal disseminated KS is associated with severe immunosuppression due to with a low CD4 count. The presentation of these two cases highlights the potentially aggressive clinical course of KS in patients with HIV/AIDS and reinforces the need for early diagnosis and rapid treatment with HAART.</description><identifier>ISSN: 1941-5923</identifier><identifier>EISSN: 1941-5923</identifier><identifier>DOI: 10.12659/AJCR.910004</identifier><identifier>PMID: 30042376</identifier><language>eng</language><publisher>United States</publisher><ispartof>The American journal of case reports, 2018-07, Vol.19, p.868-874</ispartof><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c296t-32a824e0eb3354c033d905085c71561d80c3d59affc4f35b25fc36e13eafa1533</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30042376$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Fardin, Rafaela Barbirato</creatorcontrib><creatorcontrib>Leite, Luiz Arhur Calheiros</creatorcontrib><creatorcontrib>Bezerra, Luanna Mayara Dos Santos</creatorcontrib><creatorcontrib>Alves, Priscilla Maris Pereira</creatorcontrib><creatorcontrib>Dos Santos, Layanne Lima</creatorcontrib><creatorcontrib>Salvá, Marília de Andrade</creatorcontrib><creatorcontrib>Rezende Filho, Antônio Luiz Soares Moura</creatorcontrib><creatorcontrib>Lima, Gilberto Salustiano</creatorcontrib><creatorcontrib>Matos, Juliana de Amorim</creatorcontrib><creatorcontrib>Ferreira, Sônia Maria Soares</creatorcontrib><creatorcontrib>Costa, Ducy Lily Joazeiro de Farias</creatorcontrib><title>Fatal Disseminated Kaposi's Sarcoma in Two Patients with Human Immunodeficiency Virus (HIV) InfectionFatal Disseminated Kaposi's Sarcoma in Two Patients with Human Immunodeficiency Virus (HIV) Infection</title><title>The American journal of case reports</title><addtitle>Am J Case Rep</addtitle><description>BACKGROUND Kaposi's sarcoma (KS) is a common condition in patients with human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS). In these patients, the occurrence of KS is reduced by treatment with highly active antiretroviral therapy (HAART). Fatal and disseminated KS is presented in two patients with HIV/AIDS. CASE REPORT A 25-year-old man and a 30-year-old man with HIV/AIDS presented with KS affecting the skin, oral cavity, gastrointestinal tract, liver, lungs, kidneys, adrenal glands, and bone. Both patients had a rapidly deteriorating clinical course associated with a low CD4 count and developed respiratory failure and death. CONCLUSIONS Fatal disseminated KS is associated with severe immunosuppression due to with a low CD4 count. The presentation of these two cases highlights the potentially aggressive clinical course of KS in patients with HIV/AIDS and reinforces the need for early diagnosis and rapid treatment with HAART.</description><issn>1941-5923</issn><issn>1941-5923</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><recordid>eNq9kcFKAzEURYMoVmp3riU7FZya5E3SzrJUa0cLitZuhzSTYKTJlEmG0l_0qxytil_g6l14h3sXB6ETSvqUCZ5dje7GT_2MEkLSPXREs5QmPGOw_yd3UC-Et5YggokBg0PUgRZnMBBH6H0io1zhaxuCdtbLqEt8L9dVsGcBP8taVU5i6_F8U-FHGa32MeCNja942jjpce5c46tSG6van9riha2bgM-n-eIC595oFW3l_2XkGB0YuQq693276GVyMx9Pk9nDbT4ezRLFMhETYHLIUk30EoCnigCUGeFkyNWAckHLIVFQ8kwao1IDfMm4USA0BS2NpBygiy53vaquQqi1Kda1dbLeFpQUX1aKTyvFzkqLn-7wdbN0uvyFfxzAB3jJijo</recordid><startdate>20180725</startdate><enddate>20180725</enddate><creator>Fardin, Rafaela Barbirato</creator><creator>Leite, Luiz Arhur Calheiros</creator><creator>Bezerra, Luanna Mayara Dos Santos</creator><creator>Alves, Priscilla Maris Pereira</creator><creator>Dos Santos, Layanne Lima</creator><creator>Salvá, Marília de Andrade</creator><creator>Rezende Filho, Antônio Luiz Soares Moura</creator><creator>Lima, Gilberto Salustiano</creator><creator>Matos, Juliana de Amorim</creator><creator>Ferreira, Sônia Maria Soares</creator><creator>Costa, Ducy Lily Joazeiro de Farias</creator><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20180725</creationdate><title>Fatal Disseminated Kaposi's Sarcoma in Two Patients with Human Immunodeficiency Virus (HIV) InfectionFatal Disseminated Kaposi's Sarcoma in Two Patients with Human Immunodeficiency Virus (HIV) Infection</title><author>Fardin, Rafaela Barbirato ; Leite, Luiz Arhur Calheiros ; Bezerra, Luanna Mayara Dos Santos ; Alves, Priscilla Maris Pereira ; Dos Santos, Layanne Lima ; Salvá, Marília de Andrade ; Rezende Filho, Antônio Luiz Soares Moura ; Lima, Gilberto Salustiano ; Matos, Juliana de Amorim ; Ferreira, Sônia Maria Soares ; Costa, Ducy Lily Joazeiro de Farias</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c296t-32a824e0eb3354c033d905085c71561d80c3d59affc4f35b25fc36e13eafa1533</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><toplevel>online_resources</toplevel><creatorcontrib>Fardin, Rafaela Barbirato</creatorcontrib><creatorcontrib>Leite, Luiz Arhur Calheiros</creatorcontrib><creatorcontrib>Bezerra, Luanna Mayara Dos Santos</creatorcontrib><creatorcontrib>Alves, Priscilla Maris Pereira</creatorcontrib><creatorcontrib>Dos Santos, Layanne Lima</creatorcontrib><creatorcontrib>Salvá, Marília de Andrade</creatorcontrib><creatorcontrib>Rezende Filho, Antônio Luiz Soares Moura</creatorcontrib><creatorcontrib>Lima, Gilberto Salustiano</creatorcontrib><creatorcontrib>Matos, Juliana de Amorim</creatorcontrib><creatorcontrib>Ferreira, Sônia Maria Soares</creatorcontrib><creatorcontrib>Costa, Ducy Lily Joazeiro de Farias</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><jtitle>The American journal of case reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fardin, Rafaela Barbirato</au><au>Leite, Luiz Arhur Calheiros</au><au>Bezerra, Luanna Mayara Dos Santos</au><au>Alves, Priscilla Maris Pereira</au><au>Dos Santos, Layanne Lima</au><au>Salvá, Marília de Andrade</au><au>Rezende Filho, Antônio Luiz Soares Moura</au><au>Lima, Gilberto Salustiano</au><au>Matos, Juliana de Amorim</au><au>Ferreira, Sônia Maria Soares</au><au>Costa, Ducy Lily Joazeiro de Farias</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Fatal Disseminated Kaposi's Sarcoma in Two Patients with Human Immunodeficiency Virus (HIV) InfectionFatal Disseminated Kaposi's Sarcoma in Two Patients with Human Immunodeficiency Virus (HIV) Infection</atitle><jtitle>The American journal of case reports</jtitle><addtitle>Am J Case Rep</addtitle><date>2018-07-25</date><risdate>2018</risdate><volume>19</volume><spage>868</spage><epage>874</epage><pages>868-874</pages><issn>1941-5923</issn><eissn>1941-5923</eissn><abstract>BACKGROUND Kaposi's sarcoma (KS) is a common condition in patients with human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS). In these patients, the occurrence of KS is reduced by treatment with highly active antiretroviral therapy (HAART). Fatal and disseminated KS is presented in two patients with HIV/AIDS. CASE REPORT A 25-year-old man and a 30-year-old man with HIV/AIDS presented with KS affecting the skin, oral cavity, gastrointestinal tract, liver, lungs, kidneys, adrenal glands, and bone. Both patients had a rapidly deteriorating clinical course associated with a low CD4 count and developed respiratory failure and death. CONCLUSIONS Fatal disseminated KS is associated with severe immunosuppression due to with a low CD4 count. The presentation of these two cases highlights the potentially aggressive clinical course of KS in patients with HIV/AIDS and reinforces the need for early diagnosis and rapid treatment with HAART.</abstract><cop>United States</cop><pmid>30042376</pmid><doi>10.12659/AJCR.910004</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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| source | EZB-FREE-00999 freely available EZB journals; PubMed Central; Alma/SFX Local Collection |
| title | Fatal Disseminated Kaposi's Sarcoma in Two Patients with Human Immunodeficiency Virus (HIV) InfectionFatal Disseminated Kaposi's Sarcoma in Two Patients with Human Immunodeficiency Virus (HIV) Infection |
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