Molecular mechanism for preQ 1 -II riboswitch function revealed by molecular dynamics

Riboswitches are RNA molecules that regulate gene expression using conformational change, affected by binding of small molecule ligands. A crystal structure of a ligand-bound class II preQ 1 riboswitch has been determined in a previous structural study. To gain insight into the dynamics of this ribo...

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Veröffentlicht in:	RNA (Cambridge) 2015-11, Vol.21 (11), p.1898-1907
Hauptverfasser:	Aytenfisu, Asaminew H., Liberman, Joseph A., Wedekind, Joseph E., Mathews, David H.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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