Imaging and treatment with 68 Gallium and 177 Lutetium-DOTATATE in a rare SSTR2 and ESWR1-CREM fusion positive undifferentiated round cell tumour of the lung

The authors present a 45-year-old lady with a rare undifferentiated round cell tumour of the lung with a ESWR1-CREM fusion gene that progressed despite multiple lines of therapy. The tumour was Somatostatin Receptors Type 2 (SSTR2) positive and avid on Gallium-DOTATATE imaging. This allowed for nove...

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Veröffentlicht in:BJR case reports 2023-02, Vol.9 (1), p.20220094
Hauptverfasser: Kumaran, Arjunan, Koo, Si Xuan, Yeong, Joe, Takano, Angela Maria, Farid, Mohamad, Loke, Siu Hoong, Nei, Wen Long
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container_start_page 20220094
container_title BJR case reports
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creator Kumaran, Arjunan
Koo, Si Xuan
Yeong, Joe
Takano, Angela Maria
Farid, Mohamad
Loke, Siu Hoong
Nei, Wen Long
description The authors present a 45-year-old lady with a rare undifferentiated round cell tumour of the lung with a ESWR1-CREM fusion gene that progressed despite multiple lines of therapy. The tumour was Somatostatin Receptors Type 2 (SSTR2) positive and avid on Gallium-DOTATATE imaging. This allowed for novel treatment with Peptide Receptor Radionuclide Therapy (PRRT) using Lutetium-DOTATATE after all other standard of care options were exhausted.
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title Imaging and treatment with 68 Gallium and 177 Lutetium-DOTATATE in a rare SSTR2 and ESWR1-CREM fusion positive undifferentiated round cell tumour of the lung
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