Preclinical testing on insects predicts human haematotoxic potentials

The substitution of insects for laboratory animals in toxicity testing is likely to become a reality in the framework of prescreening. Haematotoxicological studies of newly developed chemicals, such as food components, drugs, etc. performed on insects can offer advantages in, for example, environmen...

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Veröffentlicht in:	Laboratory Animals 2009-10, Vol.43 (4), p.328-332
1. Verfasser:	Berger, Josef
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Use Alternatives Animals bioassays bioethics biomedical research Blood Cells - drug effects chemical substances cytotoxicity Drug Evaluation, Preclinical - methods drugs foods Hematologic Diseases - chemically induced hematologic tests hemocytes humans insect models Insecta - drug effects insects laboratory animals leukocytes literature reviews mammals Predictive Value of Tests screening species differences Species Specificity toxic substances toxicity testing Toxicity Tests - methods validity Xenobiotics - toxicity
Online-Zugang:	Volltext
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