Toxicity of anticancer agents, growth and chemosensitivity of human tumour xenografts in a segregating stock of AF nude mice

An investigation of the usefulness of a segregating stock of nude mice [AF nude mice (AF-nu)] for screening anticancer agents was undertaken. The toxicity of anticancer agents, takes and growth rates of human tumour xenografts and chemosensitivities of xenografts in AF-nu were studied and compared w...

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Veröffentlicht in:	Laboratory animals (London) 1991-10, Vol.25 (4), p.342-347
Hauptverfasser:	Maruo, K, Emura, R, Ohnishi, Y, Endo, S, Ueyama, Y, Nomura, T
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals antineoplastic agents Antineoplastic Agents - adverse effects Cell Division Cell Line drug effects Drug Screening Assays, Antitumor drug therapy drug toxicity Female Glioma - drug therapy Glioma - pathology Glioma - veterinary growth Humans Lung Neoplasms - drug therapy Lung Neoplasms - pathology Lung Neoplasms - veterinary Male Mice Mice, Inbred BALB C Mice, Nude Neoplasm Transplantation neoplasms Neoplasms, Experimental - drug therapy Neoplasms, Experimental - pathology Stomach Neoplasms - drug therapy Stomach Neoplasms - pathology Stomach Neoplasms - veterinary Transplantation, Heterologous - mortality Transplantation, Heterologous - veterinary
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