Neither the 5-HT1A- nor the 5-HT2-Receptor Subtype Mediates the Effect of Fluvoxamine, a Selective Serotonin Reuptake Inhibitor, on Forced-Swimming-Induced Immobility in Mice

The effect of fluvoxamine, a selective serotonin (5-HT) reuptake inhibitor, was studied in the forced-swimming test, a model of depression, in mice. Fluvoxamine at 60 mg/kg, p.o. significantly decreased the immobility time in the forced-swimming test. A similar effect was observed by the selective n...

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Veröffentlicht in:	Japanese journal of pharmacology 1995, Vol.68(1), pp.71-75
Hauptverfasser:	Egawa, Takashi, Ichimaru, Yasuyuki, Imanishi, Taiichiro, Sawa, Aiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of Variance Animals Behavior, Animal - drug effects Biological and medical sciences Depression model Desipramine - pharmacology Disease Models, Animal Drug Interactions Fluvoxamine Fluvoxamine - pharmacology Forced-swimming Male Medical sciences Mice Mice, Inbred ICR Neuropharmacology Pharmacology. Drug treatments Piperazines - pharmacology Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) Psychology. Psychoanalysis. Psychiatry Psychopharmacology Receptors, Serotonin - drug effects Receptors, Serotonin - metabolism Receptors, Serotonin, 5-HT1 Ritanserin - pharmacology Selective serotonin reuptake inhibitor Serotonin Antagonists - pharmacology
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