Protective Effect of Benidipine against the Development of Glomerular Sclerosis in Experimental Nephrotic Syndrome

An experimental focal segmental glomerular sclerosis (FSGS) was induced by the combined administration of puromycin aminonucleoside (PAN) and protamine sulfate (PS). Blood collections were made on days 0, 37, 70 and 94. Urine collections were made on days 0, 24, 80 and 94. Vehicle-treated rats showe...

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Veröffentlicht in:	Japanese Journal of Pharmacology 1992, Vol.59(4), pp.461-467
Hauptverfasser:	Shirakura, Shiro, Sano, Jun-ichi, Karasawa, Akira, Kubo, Kazuhiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antihypertensive agents Benidipine Biological and medical sciences Blood Pressure - drug effects Blood Pressure - physiology Body Weight - drug effects Body Weight - physiology Calcium Channel Blockers - therapeutic use Cardiovascular system Dihydropyridines - therapeutic use Glomerulosclerosis, Focal Segmental - chemically induced Glomerulosclerosis, Focal Segmental - prevention & control Glomerulosclerosis, Focal Segmental - urine Kidney - drug effects Kidney - pathology Male Medical sciences Nephrotic syndrome Nephrotic Syndrome - complications Nephrotic Syndrome - prevention & control Nephrotic Syndrome - urine Pharmacology. Drug treatments Protamines Proteinuria - urine Puromycin Aminonucleoside Rats Rats, Sprague-Dawley Urine
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