Electrophysiological effects of KW-3049, a novel dihydropyridine type Ca antagonist, on isolated rabbit hearts, sinus nodal tissues and guinea-pig ventricular muscles

Effects of KW-3049 on electrophysiological properties of the heart were examined using Langendorff-perfused hearts and superfused sinus nodal tissues of rabbits and superfused guinea-pig ventricular muscles. In rabbit hearts, KW-3049 at concentrations above 10-7 M caused a dose-related prolongation...

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Veröffentlicht in:Folia Pharmacologica Japonica 1986, Vol.88(3), pp.179-187
Hauptverfasser: YOSHITAKE, Ikufumi, KUBO, Kazuhiro, IKEDA, Nobuo, KODAMA, Itsuo, TOYAMA, Junji, YAMADA, Kazuo
Format: Artikel
Sprache:eng ; jpn
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