Effect of KW-5805 on gastric mucus changes induced by water immersion-restraint stress and aspirin in rats

The effects of 5-[2-(diethylamino)ethyl]amino-5, 11-dihydro[1]benzoxepino[3, 4-b]pyridine trihydrochloride (KW-5805) on the changes of gastric mucus induced by stress and aspirin were studied in rats. Water immersion-restraint stress time-dependently decreased the gastric adherent mucus content and...

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Veröffentlicht in:	Folia Pharmacologica Japonica 1994, Vol.104(4), pp.293-302
Hauptverfasser:	KOSAKA, Nobuo, TANAKA, Hiroshi, ISHII, Akio, SHUTO, Katsuichi
Format:	Artikel
Sprache:	jpn
Schlagworte:	Animals Anti-Ulcer Agents - pharmacology Aspirin - adverse effects Benzoxepins - pharmacology Gastric Mucosa - metabolism Glycoproteins - metabolism Immersion Mucus - metabolism Rats Restraint, Physical Stomach Ulcer - chemically induced Stomach Ulcer - metabolism Stomach Ulcer - prevention & control Stress, Physiological - metabolism
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