BIOCHEMICAL AND STRUCTURAL REMODELING OF COLLAGEN IN THE RIGHT VENTRICULAR HYPERTROPHY INDUCED BY MONOCROTALINE

We investigated biochemical and structural changes in collagen in ventricles in right ventricular hypertrophy (RVH) induced by monocrotaline injection in Sprague-Dawley rats. Rats injected with monocrotaline showed significant RVH after 2 weeks compared with the vehicle-treated rats (controls). Afte...

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Veröffentlicht in:	JAPANESE CIRCULATION JOURNAL 1992/04/20, Vol.56(4), pp.392-403
Hauptverfasser:	HONDA, MASAAKI, YAMADA, SACHIKO, GOTO, YASUTOSHI, ISHIKAWA, SHIGENORI, YOSHIKANE, HIDEKI, ISHINAGA, YUJI, KUZUO, HIROSHI, MORIOKA, SHIGEFUMI, MORIYAMA, KATSUTOSHI
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Blood Pressure Cardiology. Vascular system Cardiomegaly - chemically induced Cardiomegaly - metabolism Cardiomegaly - physiopathology Collagen - metabolism Collagen - ultrastructure Collagen content Collagen types Disease Models, Animal Electrophoresis, Polyacrylamide Gel Heart Heart failure, cardiogenic pulmonary edema, cardiac enlargement Heart Ventricles - metabolism Male Medical sciences Microscopy, Electron, Scanning Monocrotaline Myocardium - metabolism Pulmonary hypertension Rats Rats, Inbred Strains Right ventricular hypertrophy Pressure overload Scanning electron microscopy
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