Banana juice reduces bioavailability of levodopa preparation

This study aimed to examine the effects of banana juice on levodopa bioavailability in rats. When a levodopa preparation (EC-Doparl tablets) was orally administered with banana juice made by mixing with a fresh banana and water, there were significant decreases in C(max) (17.4+/-2.5 vs. 8.6+/-3.1 mi...

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Veröffentlicht in:	Yakugaku zasshi 2005-12, Vol.125 (12), p.1009-1011
Hauptverfasser:	Ogo, Yuki, Sunagane, Nobuyoshi, Ohta, Takafumi, Uruno, Tsutomu
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Animals Antiparkinson Agents - administration & dosage Antiparkinson Agents - pharmacokinetics Biological Availability Food-Drug Interactions Levodopa - administration & dosage Levodopa - pharmacokinetics Male Musa Rats Rats, Wistar
Online-Zugang:	Volltext
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