Solid Dispersions of Benidipine Hydrochloride. I. Preparations Using Different Solvent Systems and Dissolution Properties

The solid dispersion technique has been widely utilized to improve the dissolution profile and oral bioavailability of water insoluble drugs. Benidipine hydrochloride, a calcium-antagonist, is a slightly soluble compound in a weak acid, so that its bioavailability is liable to be influenced by the g...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Chemical & pharmaceutical bulletin 1996/02/15, Vol.44(2), pp.364-371
Hauptverfasser:	SUZUKI, Hideshi, MIYAMOTO, Norifumi, MASADA, Tomoaki, HAYAKAWA, Eiji, ITO, Kunio
Format:	Artikel
Sprache:	eng
Schlagworte:	benidipine hydrochloride binary solvent mixture Biological and medical sciences dissolution rate Eudragit[○!R] E-100 General pharmacology Medical sciences Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments solid dispersion
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!