Studies on cerebral protective agents. II: Novel 4-arylpyrimidine derivatives with anti-anoxic and anti-lipid peroxidation activities

In a search for new cerebral protective agents with anti-anoxic (AA) and anti-lipid peroxidation (ALP) activities, a series of 4-arylpyrimidines, bearing an amino moiety in the C-5 position of the pyrimidine nucleus, was synthesized and tested for AA and ALP activities. Among them, 6-methyl-5-(4-met...

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Veröffentlicht in:Chemical & pharmaceutical bulletin 1992, Vol.40 (9), p.2423-2431
Hauptverfasser: KUNO, A, SUGIYAMA, Y, KATSUTA, K, SAKAI, H, TAKASUGI, H
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Sprache:eng
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