Retention Period of Amyloid β1–42 in the Brain Extracellular Fluid as the Toxicological Determinant in Freely Moving Rats

The pathological significance of amyloid-β1–42 (Aβ1–42) dynamics is poorly understood in the brain extracellular compartment. Here we test which of the concentration or the retention is critical for Aβ1–42 toxicity after injection of equal dose into dentate granule cell layer of freely moving rats....

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Veröffentlicht in:	Biological & pharmaceutical bulletin 2020/12/01, Vol.43(12), pp.1975-1978
Hauptverfasser:	Tamano, Haruna, Togo, Junichi, Sato, Yuichi, Shioya, Aoi, Tempaku, Munekazu, Takeda, Atsushi
Format:	Artikel
Sprache:	eng
Schlagworte:	amyloid β1–42 dentate gyrus long-term potentiation (LTP) freely moving rat Zn2
Online-Zugang:	Volltext
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