Antitumor β-Glucan from the Cultured Fruit Body of Agaricus blazei

Agaricus blazei is a medically important mushroom widely eaten and prescribed in Japan. Polysaccharide fractions were prepared from cultured A. blazei by repeated extraction with hot water (AgHWE), cold NaOH (AgCA), and then hot NaOH (AgHA). By chemical, enzymic, and NMR analyses, the primary struct...

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Veröffentlicht in:	Biological & pharmaceutical bulletin 2001, Vol.24(7), pp.820-828
Hauptverfasser:	OHNO, Naohito, FURUKAWA, Mai, MIURA, Noriko N., ADACHI, Yoshiyuki, MOTOI, Masuro, YADOMAE, Toshiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Agaricus - chemistry Agaricus blazei Animals Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - isolation & purification Antibiotics, Antineoplastic - chemistry Antibiotics, Antineoplastic - isolation & purification Antibiotics, Antineoplastic - pharmacology Antineoplastic agents antitumor activity Biological and medical sciences Carbohydrates - chemistry Chemotherapy Drug Screening Assays, Antitumor Glucan Endo-1,3-beta-D-Glucosidase Glucans - chemistry Glucans - isolation & purification Glucans - pharmacology Hydrolysis immunomodulation Immunomodulators Limulus Test Magnetic Resonance Spectroscopy Male Medical sciences Mice Mice, Inbred ICR Pharmacology. Drug treatments Sarcoma 180 - drug therapy Sodium Hypochlorite - chemistry Terpenes - chemistry Terpenes - isolation & purification Tumor Cells, Cultured Vasculitis - chemically induced β-glucan
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