A New One-pot Synthesis of α-Amino Phosphonates Catalyzed by Butyldimethyl(1-phenylethyl)ammonium Bromide

Butyldimethyl(1-phenylethyl)ammonium bromide is found to be an efficient catalyst for the three-component reaction of an aldehyde, aromatic amine, and trimethylphosphite in refluxing CH2Cl2 to afford corresponding α-amino phosphonate in high yield.

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Veröffentlicht in:Chemistry letters 2005-03, Vol.34 (3), p.444-445
Hauptverfasser: Reddy, K. Rosi, Reddy, K. Srinivasa, Reddy, Ch. Venkateshwar, Mahesh, M, Raju, P. V. K, Reddy, V. V. Narayana
Format: Artikel
Sprache:eng
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Zusammenfassung:Butyldimethyl(1-phenylethyl)ammonium bromide is found to be an efficient catalyst for the three-component reaction of an aldehyde, aromatic amine, and trimethylphosphite in refluxing CH2Cl2 to afford corresponding α-amino phosphonate in high yield.
ISSN:0366-7022
1348-0715
DOI:10.1246/cl.2005.444