Flow-based Biosensing System for Glucose Fabricated by Using Track-etched Microporous Membrane Electrodes

The new type of amperometric biosensor described herein, which was fabricated by using a track-etched microporous membrane electrode for glucose detection, comprises a prereactor electrode, a detector electrode, and an immobilized enzyme reactor sandwiched between these electrodes. Because the sampl...

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Veröffentlicht in:Chemistry letters 2013-10, Vol.42 (10), p.1317-1319
Hauptverfasser: Mizuguchi, Hitoshi, Sakurai, Jun, Kinoshita, Yuki, Iiyama, Masamitsu, Kijima, Tatsuro, Tachibana, Kazuhiro, Nishina, Tatsuo, Shida, Junichi
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container_end_page 1319
container_issue 10
container_start_page 1317
container_title Chemistry letters
container_volume 42
creator Mizuguchi, Hitoshi
Sakurai, Jun
Kinoshita, Yuki
Iiyama, Masamitsu
Kijima, Tatsuro
Tachibana, Kazuhiro
Nishina, Tatsuo
Shida, Junichi
description The new type of amperometric biosensor described herein, which was fabricated by using a track-etched microporous membrane electrode for glucose detection, comprises a prereactor electrode, a detector electrode, and an immobilized enzyme reactor sandwiched between these electrodes. Because the sample solution flows through this system, the interferents are electrolyzed completely at the prereactor, positioned upstream of the enzyme reactor. The increased current response at the detector electrode derives solely from oxidation of hydrogen peroxide produced in the enzymatic reaction. Sensitive and selective response toward glucose detection was obtained with no other catalytic material such as peroxidase or an electron mediator.
doi_str_mv 10.1246/cl.130594
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title Flow-based Biosensing System for Glucose Fabricated by Using Track-etched Microporous Membrane Electrodes
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