VEGF expression in human macrophages is NF-κB-dependent: studies using adenoviruses expressing the endogenous NF-κB inhibitor IκBα and a kinase-defective form of the IκB kinase 2

Vascular endothelial growth factor (VEGF) is the most endothelial cell-specific angiogenic factor characterised to date, and it is produced by a variety of cell types. In macrophages, VEGF has been shown to be upregulated by the inflammatory mediator lipopolysaccharide (LPS) and by engagement of CD4...

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Veröffentlicht in:Journal of cell science 2003-02, Vol.116 (4), p.665-674
Hauptverfasser: Kiriakidis, Serafim, Andreakos, Evangelos, Monaco, Claudia, Foxwell, Brian, Feldmann, Marc, Paleolog, Ewa
Format: Artikel
Sprache:eng
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