VEGF expression in human macrophages is NF-κB-dependent: studies using adenoviruses expressing the endogenous NF-κB inhibitor IκBα and a kinase-defective form of the IκB kinase 2
Vascular endothelial growth factor (VEGF) is the most endothelial cell-specific angiogenic factor characterised to date, and it is produced by a variety of cell types. In macrophages, VEGF has been shown to be upregulated by the inflammatory mediator lipopolysaccharide (LPS) and by engagement of CD4...
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Veröffentlicht in: | Journal of cell science 2003-02, Vol.116 (4), p.665-674 |
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Hauptverfasser: | , , , , , |
Format: | Artikel |
Sprache: | eng |
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