Lymphocytic Hypophysitis with Involvement of the Cavernous Sinus and Hypothalamus

Two cases of lymphocytic hypophysitis are reported, in which hypothalamic involvement causing diabetes insipidus was a prominent clinical feature. In one case, a man had clinical and radiological evidence of the involvement of the cavernous sinus. This represents the second reported case of a man wi...

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Veröffentlicht in:Neurosurgery 1991-03, Vol.28 (3), p.440-444
Hauptverfasser: Nussbaum, Charles E., Shige-Hisa, Okawara, Jacobs, Laurence S.
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Shige-Hisa, Okawara
Jacobs, Laurence S.
description Two cases of lymphocytic hypophysitis are reported, in which hypothalamic involvement causing diabetes insipidus was a prominent clinical feature. In one case, a man had clinical and radiological evidence of the involvement of the cavernous sinus. This represents the second reported case of a man with lymphocytic hypophysitis. A transsphenoidal biopsy established the diagnosis in both cases. Neither the involvement of the cavernous sinus nor permanent diabetes insipidus has been reported previously. A review of the literature is provided.
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