Local Control of Recurrent Clival and Sacral Chordoma after Interstitial Irradiation with Iodine-125: New Techniques for Treatment of Recurrent or Unresectable Chordomas

Using new 125I brachytherapy techniques, we were able to deliver safely a tumor volume dose of 16,000 rads to a previous irradiated, large, recurrent sacral chordoma by means of the intraoperative interstitial implantation of 229 low activity 125I seeds and 40,000 rads to a previously irradiated, sm...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Neurosurgery 1988-03, Vol.22 (3), p.479-483
Hauptverfasser: Kumar, Pradeep P., Good, Roger R., Skultety, F. Miles, Leibrock, Lyal G.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 483
container_issue 3
container_start_page 479
container_title Neurosurgery
container_volume 22
creator Kumar, Pradeep P.
Good, Roger R.
Skultety, F. Miles
Leibrock, Lyal G.
description Using new 125I brachytherapy techniques, we were able to deliver safely a tumor volume dose of 16,000 rads to a previous irradiated, large, recurrent sacral chordoma by means of the intraoperative interstitial implantation of 229 low activity 125I seeds and 40,000 rads to a previously irradiated, small, recurrent clival chordoma by means of the transnasal needle implantation of two high activity 125I seeds. Iodine-125 brachytherapy was followed by regression of tumor, lessening of symptoms, and bony recalcification in both cases. (Neurosurgery 22:479-483, 1988)
doi_str_mv 10.1227/00006123-198803000-00005
format Article
fullrecord <record><control><sourceid>crossref_osti_</sourceid><recordid>TN_cdi_crossref_primary_10_1227_00006123_198803000_00005</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>10_1227_00006123_198803000_00005</sourcerecordid><originalsourceid>FETCH-LOGICAL-c2495-cd7890c2326e6ac108d4cbed1e370c31202ca5efe4d15739b78491d65a5ca5993</originalsourceid><addsrcrecordid>eNpVUdtKAzEUDKJgvfxD8H01193ENyleCkVBK_i2pMlZGtkmmkTFT_IvTb2BeUg4M8OZCYMQpuSYMtadkHpaynhDtVKE16nZQHILTahkohFEkG00IVSohuv2YRft5fxICG1FpyboYx6tGfE0hpLiiOOAb8G-pASh4OnoXytngsN3xqaNbBWTi2uDzVAg4Vmody6--MrNUjLOm-JjwG--rPAsOh-goUye4mt4wwuwq-CfXyDjISa8SGDKeuPzz7Qy9yFBBlvMcoQ_y3yAdgYzZjj8effR_cX5YnrVzG8uZ9OzeWOZ0LKxrlOaWMZZC62xlCgn7BIcBd4RyykjzBoJAwhHZcf1slNCU9dKIyuuNd9HR997Y_1Zn60vNbeNIdREfUdaRTSvIvUtsinmnGDon5Jfm_TeU9Jveul_e-n_evmCJP8EqN2Cuw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Local Control of Recurrent Clival and Sacral Chordoma after Interstitial Irradiation with Iodine-125: New Techniques for Treatment of Recurrent or Unresectable Chordomas</title><source>Journals@Ovid Complete</source><creator>Kumar, Pradeep P. ; Good, Roger R. ; Skultety, F. Miles ; Leibrock, Lyal G.</creator><creatorcontrib>Kumar, Pradeep P. ; Good, Roger R. ; Skultety, F. Miles ; Leibrock, Lyal G. ; Univ. of Nebraska College of Medicine, Omaha (USA)</creatorcontrib><description>Using new 125I brachytherapy techniques, we were able to deliver safely a tumor volume dose of 16,000 rads to a previous irradiated, large, recurrent sacral chordoma by means of the intraoperative interstitial implantation of 229 low activity 125I seeds and 40,000 rads to a previously irradiated, small, recurrent clival chordoma by means of the transnasal needle implantation of two high activity 125I seeds. Iodine-125 brachytherapy was followed by regression of tumor, lessening of symptoms, and bony recalcification in both cases. (Neurosurgery 22:479-483, 1988)</description><identifier>ISSN: 0148-396X</identifier><identifier>EISSN: 1524-4040</identifier><identifier>DOI: 10.1227/00006123-198803000-00005</identifier><language>eng</language><publisher>United States</publisher><subject>550603 - Medicine- External Radiation in Therapy- (1980-) ; BETA DECAY RADIOISOTOPES ; BODY ; DAYS LIVING RADIOISOTOPES ; DISEASES ; DOSES ; ELECTRON CAPTURE RADIOISOTOPES ; IMPLANTS ; INTERMEDIATE MASS NUCLEI ; IODINE 125 ; IODINE ISOTOPES ; ISOTOPES ; MEDICINE ; NEOPLASMS ; NUCLEAR MEDICINE ; NUCLEI ; ODD-EVEN NUCLEI ; ORGANS ; RADIATION DOSES ; RADIATION SOURCE IMPLANTS ; RADIATION SOURCES ; RADIOISOTOPES ; RADIOLOGY ; RADIOLOGY AND NUCLEAR MEDICINE ; RADIOTHERAPY ; SKELETON ; SKULL ; THERAPY</subject><ispartof>Neurosurgery, 1988-03, Vol.22 (3), p.479-483</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2495-cd7890c2326e6ac108d4cbed1e370c31202ca5efe4d15739b78491d65a5ca5993</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,885,27924,27925</link.rule.ids><backlink>$$Uhttps://www.osti.gov/biblio/7068093$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>Kumar, Pradeep P.</creatorcontrib><creatorcontrib>Good, Roger R.</creatorcontrib><creatorcontrib>Skultety, F. Miles</creatorcontrib><creatorcontrib>Leibrock, Lyal G.</creatorcontrib><creatorcontrib>Univ. of Nebraska College of Medicine, Omaha (USA)</creatorcontrib><title>Local Control of Recurrent Clival and Sacral Chordoma after Interstitial Irradiation with Iodine-125: New Techniques for Treatment of Recurrent or Unresectable Chordomas</title><title>Neurosurgery</title><description>Using new 125I brachytherapy techniques, we were able to deliver safely a tumor volume dose of 16,000 rads to a previous irradiated, large, recurrent sacral chordoma by means of the intraoperative interstitial implantation of 229 low activity 125I seeds and 40,000 rads to a previously irradiated, small, recurrent clival chordoma by means of the transnasal needle implantation of two high activity 125I seeds. Iodine-125 brachytherapy was followed by regression of tumor, lessening of symptoms, and bony recalcification in both cases. (Neurosurgery 22:479-483, 1988)</description><subject>550603 - Medicine- External Radiation in Therapy- (1980-)</subject><subject>BETA DECAY RADIOISOTOPES</subject><subject>BODY</subject><subject>DAYS LIVING RADIOISOTOPES</subject><subject>DISEASES</subject><subject>DOSES</subject><subject>ELECTRON CAPTURE RADIOISOTOPES</subject><subject>IMPLANTS</subject><subject>INTERMEDIATE MASS NUCLEI</subject><subject>IODINE 125</subject><subject>IODINE ISOTOPES</subject><subject>ISOTOPES</subject><subject>MEDICINE</subject><subject>NEOPLASMS</subject><subject>NUCLEAR MEDICINE</subject><subject>NUCLEI</subject><subject>ODD-EVEN NUCLEI</subject><subject>ORGANS</subject><subject>RADIATION DOSES</subject><subject>RADIATION SOURCE IMPLANTS</subject><subject>RADIATION SOURCES</subject><subject>RADIOISOTOPES</subject><subject>RADIOLOGY</subject><subject>RADIOLOGY AND NUCLEAR MEDICINE</subject><subject>RADIOTHERAPY</subject><subject>SKELETON</subject><subject>SKULL</subject><subject>THERAPY</subject><issn>0148-396X</issn><issn>1524-4040</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1988</creationdate><recordtype>article</recordtype><recordid>eNpVUdtKAzEUDKJgvfxD8H01193ENyleCkVBK_i2pMlZGtkmmkTFT_IvTb2BeUg4M8OZCYMQpuSYMtadkHpaynhDtVKE16nZQHILTahkohFEkG00IVSohuv2YRft5fxICG1FpyboYx6tGfE0hpLiiOOAb8G-pASh4OnoXytngsN3xqaNbBWTi2uDzVAg4Vmody6--MrNUjLOm-JjwG--rPAsOh-goUye4mt4wwuwq-CfXyDjISa8SGDKeuPzz7Qy9yFBBlvMcoQ_y3yAdgYzZjj8effR_cX5YnrVzG8uZ9OzeWOZ0LKxrlOaWMZZC62xlCgn7BIcBd4RyykjzBoJAwhHZcf1slNCU9dKIyuuNd9HR997Y_1Zn60vNbeNIdREfUdaRTSvIvUtsinmnGDon5Jfm_TeU9Jveul_e-n_evmCJP8EqN2Cuw</recordid><startdate>19880301</startdate><enddate>19880301</enddate><creator>Kumar, Pradeep P.</creator><creator>Good, Roger R.</creator><creator>Skultety, F. Miles</creator><creator>Leibrock, Lyal G.</creator><scope>AAYXX</scope><scope>CITATION</scope><scope>OTOTI</scope></search><sort><creationdate>19880301</creationdate><title>Local Control of Recurrent Clival and Sacral Chordoma after Interstitial Irradiation with Iodine-125: New Techniques for Treatment of Recurrent or Unresectable Chordomas</title><author>Kumar, Pradeep P. ; Good, Roger R. ; Skultety, F. Miles ; Leibrock, Lyal G.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2495-cd7890c2326e6ac108d4cbed1e370c31202ca5efe4d15739b78491d65a5ca5993</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1988</creationdate><topic>550603 - Medicine- External Radiation in Therapy- (1980-)</topic><topic>BETA DECAY RADIOISOTOPES</topic><topic>BODY</topic><topic>DAYS LIVING RADIOISOTOPES</topic><topic>DISEASES</topic><topic>DOSES</topic><topic>ELECTRON CAPTURE RADIOISOTOPES</topic><topic>IMPLANTS</topic><topic>INTERMEDIATE MASS NUCLEI</topic><topic>IODINE 125</topic><topic>IODINE ISOTOPES</topic><topic>ISOTOPES</topic><topic>MEDICINE</topic><topic>NEOPLASMS</topic><topic>NUCLEAR MEDICINE</topic><topic>NUCLEI</topic><topic>ODD-EVEN NUCLEI</topic><topic>ORGANS</topic><topic>RADIATION DOSES</topic><topic>RADIATION SOURCE IMPLANTS</topic><topic>RADIATION SOURCES</topic><topic>RADIOISOTOPES</topic><topic>RADIOLOGY</topic><topic>RADIOLOGY AND NUCLEAR MEDICINE</topic><topic>RADIOTHERAPY</topic><topic>SKELETON</topic><topic>SKULL</topic><topic>THERAPY</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kumar, Pradeep P.</creatorcontrib><creatorcontrib>Good, Roger R.</creatorcontrib><creatorcontrib>Skultety, F. Miles</creatorcontrib><creatorcontrib>Leibrock, Lyal G.</creatorcontrib><creatorcontrib>Univ. of Nebraska College of Medicine, Omaha (USA)</creatorcontrib><collection>CrossRef</collection><collection>OSTI.GOV</collection><jtitle>Neurosurgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kumar, Pradeep P.</au><au>Good, Roger R.</au><au>Skultety, F. Miles</au><au>Leibrock, Lyal G.</au><aucorp>Univ. of Nebraska College of Medicine, Omaha (USA)</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Local Control of Recurrent Clival and Sacral Chordoma after Interstitial Irradiation with Iodine-125: New Techniques for Treatment of Recurrent or Unresectable Chordomas</atitle><jtitle>Neurosurgery</jtitle><date>1988-03-01</date><risdate>1988</risdate><volume>22</volume><issue>3</issue><spage>479</spage><epage>483</epage><pages>479-483</pages><issn>0148-396X</issn><eissn>1524-4040</eissn><abstract>Using new 125I brachytherapy techniques, we were able to deliver safely a tumor volume dose of 16,000 rads to a previous irradiated, large, recurrent sacral chordoma by means of the intraoperative interstitial implantation of 229 low activity 125I seeds and 40,000 rads to a previously irradiated, small, recurrent clival chordoma by means of the transnasal needle implantation of two high activity 125I seeds. Iodine-125 brachytherapy was followed by regression of tumor, lessening of symptoms, and bony recalcification in both cases. (Neurosurgery 22:479-483, 1988)</abstract><cop>United States</cop><doi>10.1227/00006123-198803000-00005</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0148-396X
ispartof Neurosurgery, 1988-03, Vol.22 (3), p.479-483
issn 0148-396X
1524-4040
language eng
recordid cdi_crossref_primary_10_1227_00006123_198803000_00005
source Journals@Ovid Complete
subjects 550603 - Medicine- External Radiation in Therapy- (1980-)
BETA DECAY RADIOISOTOPES
BODY
DAYS LIVING RADIOISOTOPES
DISEASES
DOSES
ELECTRON CAPTURE RADIOISOTOPES
IMPLANTS
INTERMEDIATE MASS NUCLEI
IODINE 125
IODINE ISOTOPES
ISOTOPES
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIATION DOSES
RADIATION SOURCE IMPLANTS
RADIATION SOURCES
RADIOISOTOPES
RADIOLOGY
RADIOLOGY AND NUCLEAR MEDICINE
RADIOTHERAPY
SKELETON
SKULL
THERAPY
title Local Control of Recurrent Clival and Sacral Chordoma after Interstitial Irradiation with Iodine-125: New Techniques for Treatment of Recurrent or Unresectable Chordomas
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-20T16%3A52%3A02IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-crossref_osti_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Local%20Control%20of%20Recurrent%20Clival%20and%20Sacral%20Chordoma%20after%20Interstitial%20Irradiation%20with%20Iodine-125:%20New%20Techniques%20for%20Treatment%20of%20Recurrent%20or%20Unresectable%20Chordomas&rft.jtitle=Neurosurgery&rft.au=Kumar,%20Pradeep%20P.&rft.aucorp=Univ.%20of%20Nebraska%20College%20of%20Medicine,%20Omaha%20(USA)&rft.date=1988-03-01&rft.volume=22&rft.issue=3&rft.spage=479&rft.epage=483&rft.pages=479-483&rft.issn=0148-396X&rft.eissn=1524-4040&rft_id=info:doi/10.1227/00006123-198803000-00005&rft_dat=%3Ccrossref_osti_%3E10_1227_00006123_198803000_00005%3C/crossref_osti_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true