Local Control of Recurrent Clival and Sacral Chordoma after Interstitial Irradiation with Iodine-125: New Techniques for Treatment of Recurrent or Unresectable Chordomas
Using new 125I brachytherapy techniques, we were able to deliver safely a tumor volume dose of 16,000 rads to a previous irradiated, large, recurrent sacral chordoma by means of the intraoperative interstitial implantation of 229 low activity 125I seeds and 40,000 rads to a previously irradiated, sm...
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Veröffentlicht in: | Neurosurgery 1988-03, Vol.22 (3), p.479-483 |
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creator | Kumar, Pradeep P. Good, Roger R. Skultety, F. Miles Leibrock, Lyal G. |
description | Using new 125I brachytherapy techniques, we were able to deliver safely a tumor volume dose of 16,000 rads to a previous irradiated, large, recurrent sacral chordoma by means of the intraoperative interstitial implantation of 229 low activity 125I seeds and 40,000 rads to a previously irradiated, small, recurrent clival chordoma by means of the transnasal needle implantation of two high activity 125I seeds. Iodine-125 brachytherapy was followed by regression of tumor, lessening of symptoms, and bony recalcification in both cases. (Neurosurgery 22:479-483, 1988) |
doi_str_mv | 10.1227/00006123-198803000-00005 |
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Miles</creatorcontrib><creatorcontrib>Leibrock, Lyal G.</creatorcontrib><creatorcontrib>Univ. of Nebraska College of Medicine, Omaha (USA)</creatorcontrib><collection>CrossRef</collection><collection>OSTI.GOV</collection><jtitle>Neurosurgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kumar, Pradeep P.</au><au>Good, Roger R.</au><au>Skultety, F. Miles</au><au>Leibrock, Lyal G.</au><aucorp>Univ. of Nebraska College of Medicine, Omaha (USA)</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Local Control of Recurrent Clival and Sacral Chordoma after Interstitial Irradiation with Iodine-125: New Techniques for Treatment of Recurrent or Unresectable Chordomas</atitle><jtitle>Neurosurgery</jtitle><date>1988-03-01</date><risdate>1988</risdate><volume>22</volume><issue>3</issue><spage>479</spage><epage>483</epage><pages>479-483</pages><issn>0148-396X</issn><eissn>1524-4040</eissn><abstract>Using new 125I brachytherapy techniques, we were able to deliver safely a tumor volume dose of 16,000 rads to a previous irradiated, large, recurrent sacral chordoma by means of the intraoperative interstitial implantation of 229 low activity 125I seeds and 40,000 rads to a previously irradiated, small, recurrent clival chordoma by means of the transnasal needle implantation of two high activity 125I seeds. Iodine-125 brachytherapy was followed by regression of tumor, lessening of symptoms, and bony recalcification in both cases. (Neurosurgery 22:479-483, 1988)</abstract><cop>United States</cop><doi>10.1227/00006123-198803000-00005</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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subjects | 550603 - Medicine- External Radiation in Therapy- (1980-) BETA DECAY RADIOISOTOPES BODY DAYS LIVING RADIOISOTOPES DISEASES DOSES ELECTRON CAPTURE RADIOISOTOPES IMPLANTS INTERMEDIATE MASS NUCLEI IODINE 125 IODINE ISOTOPES ISOTOPES MEDICINE NEOPLASMS NUCLEAR MEDICINE NUCLEI ODD-EVEN NUCLEI ORGANS RADIATION DOSES RADIATION SOURCE IMPLANTS RADIATION SOURCES RADIOISOTOPES RADIOLOGY RADIOLOGY AND NUCLEAR MEDICINE RADIOTHERAPY SKELETON SKULL THERAPY |
title | Local Control of Recurrent Clival and Sacral Chordoma after Interstitial Irradiation with Iodine-125: New Techniques for Treatment of Recurrent or Unresectable Chordomas |
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