Single Dose Analgesic Efficacy of Tapentadol in Postsurgical Dental Pain : The Results of a Randomized, Double-Blind, Placebo-Controlled Study

Tapentadol is a novel, centrally acting analgesic with two modes of action, combining mu-opioid agonism and norepinephrine reuptake inhibition in a single molecule. We compared the efficacy and tolerability of tapentadol and a standard dose of morphine with placebo in a model of moderate-to-severe p...

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Veröffentlicht in:	Anesthesia and analgesia 2008-12, Vol.107 (6), p.2048-2055
Hauptverfasser:	KLEINERT, Regina, LANGE, Claudia, STEUP, Achim, BLACK, Peter, GOLDBERG, Jutta, DESJARDINS, Paul
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Analgesics - therapeutic use Anesthesia Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Double-Blind Method Female Humans Ibuprofen - therapeutic use Male Medical sciences Morphine - therapeutic use Pain, Postoperative - drug therapy Phenols - adverse effects Phenols - therapeutic use Receptors, Opioid, mu - agonists Toothache - drug therapy
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